Evidence map›Paper›PMID 30555549›Full record

ArticleTheranostics2018

Awakening p53

Zhenyuan Bian, Jin Yan, Simeng Wang, Yijie Li, Yi Guo, Bohan Ma, Hao Guo, Zhijie Lei, Chun Yin, Yi Zhou and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Bringing p53 Back: A Prion-Powered Attack on Retinoblastoma.International journal of biological sciences · 2025
    Article
  4. Blocking interplay between TERT and c-Myc: a new therapeutic strategy forInternational journal of biological sciences · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Nanomedicines Targeting Metabolism in the Tumor Microenvironment.Frontiers in bioengineering and biotechnology · 2022
    Review
  14. Article
  15. Assembling p53 Activating Peptide With CeOFrontiers in bioengineering and biotechnology · 2022
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Zhenyuan BianDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China.
Jin YanDepartment of Biologic and Materials Sciences, Department of Biomedical Engineering, Macromolecular Science and Engineering Center, Department of Materials Science and Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
Simeng WangKey Laboratory for Tumor Precision Medicine of Shaanxi Province, and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Yijie LiDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China.
Yi GuoFrontier Institute of Science and Technology, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, Xi'an 710049, China.
Bohan MaCenter for Translational Medicine, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Hao GuoFourth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Zhijie LeiFourth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Chun YinFourth Military Medical University, Xi'an 710032, Shaanxi Province, China.
Yi ZhouDepartment of Infectious Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Min LiuDepartment of Infectious Diseases, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Kaishan TaoDepartment of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, China.
Peng HouKey Laboratory for Tumor Precision Medicine of Shaanxi Province, and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Wangxiao HeCenter for Translational Medicine, Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Air Force Medical University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CNUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides are a rapidly growing class of therapeutics with many advantages over conventional small molecule drugs. Dextrorotary (D)-peptides, with increased enzymatic stability and prolonged plasma half-life in comparison with natural L-peptides, are considered to have great potential as recognition molecules and therapeutic agents. However, the

Indexed as

AnimalsAntineoplastic AgentsBiological ProductsColorectal NeoplasmsDisease Models, AnimalDrug CarriersDrug-Related Side Effects and Adverse ReactionsHCT116 CellsHeterograftsHumansMetal NanoparticlesMice, Inbred BALB CMice, NudeMolecular Targeted TherapyNanomedicineNeoplasm TransplantationAntineoplastic AgentsBiological ProductsDrug CarriersPeptidesTumor Suppressor Protein p53biosafetydextrorotary peptidegold nanoparticlep53ultra-small nanoparticle

Identifiers

PMID30555549
PMCPMC6276095
OpenAlexW2898918079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.