Evidence map›Paper›PMID 30555475›Full record

ArticleFrontiers in immunology2018

Arginase-1 Is Responsible for IL-13-Mediated Susceptibility to

Mahin Abad Dar, Christoph Hölscher

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. TPx Protein ofPathogens (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Immunopathogenesis inFrontiers in immunology · 2023
    Review
  8. Host genetic backgrounds: the key to determining parasite-host adaptation.Frontiers in cellular and infection microbiology · 2023
    Review
  9. Article
  10. Review
  11. Myeloid-Derived Suppressor Cells inFrontiers in cellular and infection microbiology · 2021
    Review
  12. Article
  13. Frontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mahin Abad DarInfection Immunology, Research Center Borstel, Borstel, Germany.
Christoph HölscherInfection Immunology, Research Center Borstel, Borstel, Germany.
Research Center Borstel - Leibniz Lung Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arginase-1 (Arg-1) is a marker for alternatively activated macrophages (AAM) and is mainly induced by the type 2 cytokines interleukin (IL)-4 and IL-13 through the common IL-4 receptor-alpha (Rα) subunit. Both, Arg-1 and AAM undermine macrophage effector functions against intracellular parasites and are therefore implicated in the susceptibility to infection with

Indexed as

AnimalsArginaseChagas DiseaseDisease SusceptibilityInterleukin-13Interleukin-4 Receptor alpha SubunitMiceMice, Inbred BALB CMice, TransgenicReceptors, Cell SurfaceTrypanosoma cruziArg1 protein, mouseArginaseIl4ra protein, mouseInterleukin-13Interleukin-4 Receptor alpha SubunitReceptors, Cell Surfacearginase-1Chagas diseaseinterleukin-13macrophage-cellTrypanosoma cruzi

Identifiers

PMID30555475
PMCPMC6281981
OpenAlexW2902932959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.