Evidence map›Paper›PMID 30555431›Full record

ArticleFrontiers in microbiology2018

Modification Targeting the "Rana Box" Motif of a Novel Nigrocin Peptide From

Kaifan Bao, Weiyuan Yuan, Chengbang Ma, Xi Yu, Lei Wang, Min Hong, Xinping Xi, Mei Zhou, Tianbao Chen

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Small Natural Cyclic Peptides from DBAASP Database.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Progressive Design of a Ranatuerin-2 Peptide fromAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Microbiology spectrum · 2021
    Article
  14. Article
  15. Article
  16. Frontiers in microbiology · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Brevinin-2GHk fromAntibiotics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaifan BaoJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China.
Weiyuan YuanJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China.
Chengbang MaNatural Drug Discovery Group, School of Pharmacy, Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, United Kingdom.
Xi YuNanjing Pharmaceutical Co., Ltd., Nanjing, China.
Lei WangNatural Drug Discovery Group, School of Pharmacy, Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, United Kingdom.
Min HongJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China.
Xinping XiNatural Drug Discovery Group, School of Pharmacy, Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, United Kingdom.
Mei ZhouNatural Drug Discovery Group, School of Pharmacy, Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, United Kingdom.
Tianbao ChenNatural Drug Discovery Group, School of Pharmacy, Faculty of Medicine, Health and Life Sciences, Queen's University Belfast, Belfast, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Public health is confronting the threat caused by antibiotic resistance and this means new antibacterial strategies must be developed urgently. Antimicrobial peptides (AMPs) have been considered as promising therapeutic candidates against infection in the post-antibiotic era. In this paper, we dismissed the significance of "Rana box" in the natural nigrocin-HL identified from skin secretion of

Indexed as

antibiotic resistancemodificationMRSAnigrocinpneumoniaRana box

Identifiers

PMID30555431
PMCPMC6280737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.