Evidence map›Paper›PMID 30555357›Full record

ArticleFrontiers in psychiatry2018

Early Life Abuse Moderates the Effects of Intranasal Oxytocin on Symptoms of Premenstrual Dysphoric Disorder: Preliminary Evidence From a Placebo-Controlled Trial.

Erin C Walsh, Tory A Eisenlohr-Moul, Cort A Pedersen, David R Rubinow, Susan S Girdler, Gabriel S Dichter

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05282277 (Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and Psychosis), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05282277 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

Examining the Effects of Estradiol on Neural and Molecular Response to Rewards in Perimenopausal-Onset Anhedonia and Psychosis

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2022 to 2026Enrolled103ConditionsDepression, Psychosis, AnhedoniaArmsTransdermal Estradiol, Micronized Progesterone, Matching Placebo Patch, Raclopride C11
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Close encounters with oxytocin.Comprehensive psychoneuroendocrinology · 2023
    Review
  4. Article
  5. Oxytocin and love: Myths, metaphors and mysteries.Comprehensive psychoneuroendocrinology · 2022
    Review
  6. Review
  7. Is Oxytocin "Nature's Medicine"?Pharmacological reviews · 2020
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Erin C WalshDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
Tory A Eisenlohr-MoulDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
Cort A PedersenDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
David R RubinowDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
Susan S GirdlerDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
Gabriel S DichterDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States.
University of North Carolina at Chapel Hill · US

Funding

UNC Research Fellowship in Complementary and Alternative MedicineT32AT003378 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Keturah Ruth Faurot, Susan Gaylord · 2007 to 2026
$7.8M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)KL2TR001109 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$5.7M
Intervention for Menstrual Mood Disorders & Early Life Abuse: Biopsych MechanismsR01MH099076 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GIRDLER, SUSAN S. · 2013 to 2017
$3.3M
Postdoctoral Training in Reproductive Mood DisordersT32MH093315 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN Scott GIRDLER, David R. Rubinow · 2012 to 2026
$2.8M
Ovarian Hormone Withdrawal and Suicide Risk: An Experimental ApproachR00MH109667 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI EISENLOHR-MOUL, TORY ANNE · 2018 to 2020
$747k
Ovarian Hormone Withdrawal and Suicide Risk: An Experimental ApproachK99MH109667 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EISENLOHR-MOUL, TORY ANNE · 2016 to 2017
$164k
NCATS NIH HHS KL2 TR001109NCCIH NIH HHS T32 AT003378NIMH NIH HHS K99 MH109667NIMH NIH HHS R00 MH109667NIMH NIH HHS R01 MH099076NIMH NIH HHS T32 MH093315
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

early life abuseemotional symptomsinterpersonal symptomsoxytocinPMDD

Identifiers

PMID30555357
PMCPMC6282546
OpenAlexW2902046767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.