Evidence map›Paper›PMID 30555281›Full record

ArticleCurrent anesthesiology reports2018

An update on postoperative delirium: Clinical features, neuropathogenesis, and perioperative management.

Seyed A Safavynia, Sona Arora, Kane O Pryor, Paul S García

Abstract read
In one paragraph

Article in Current anesthesiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  20. Deconstructing delirium in the post anaesthesia care unit.Frontiers in aging neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seyed A SafavyniaDepartment of Anesthesiology, Weill Cornell Medical College, New York, NY, USA.
Sona AroraDepartment of Anesthesiology, Emory University, Atlanta, GA, USA.
Kane O PryorDepartment of Anesthesiology, Weill Cornell Medical College, New York, NY, USA.
Paul S GarcíaDepartment of Anesthesiology, Emory University, Atlanta, GA, USA.

Funding

Effects of Antiretrovirals on Neuronal Health: Screening ARVs for NeurotoxicityIK2BX001677 · VA · VETERANS HEALTH ADMINISTRATION · PI GARCIA, PAUL S · 2014 to 2018
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BLRD VA IK2 BX001677
6 · The paper itself

Abstract

Purpose of Review: We present a focused review on postoperative delirium for anesthesiologists, encompassing clinical features, neuropathogenesis, and clinical identification and management strategies based on risk factors and current delirium treatments. Recent Findings: The literature on postoperative delirium is dominated by non-experimental studies. We review delirium phenotypes, diagnostic criteria, and present standard nomenclature based on current literature. Disruption of cortical integration of complex information (CICI) may provide a framework to understand the neuropathogenesis of postoperative delirium, as well as risk factors and clinical modifiers in the perioperative period. We further divide risk factors into patient factors, surgical factors, and medical/pharmacological factors, and present specific considerations for each in the preoperative, intraoperative, and postoperative periods. Summary: Postoperative delirium is prevalent, poorly understood, and often missed with current screening techniques. Proper identification of risk factors is useful for perioperative interventions and can help tailor patient-specific management strategies.

Indexed as

AgingAnesthesiologyCortical integration of complex information (CICI)Electroencephalography (EEG)Functional connectivityPostoperative delirium

Identifiers

PMID30555281
PMCPMC6290904

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.