Evidence map›Paper›PMID 30555065›Full record

ArticleJournal of genetics2018

Roles of

Cuifang Chang, Lingling Xi, Jihong Zhang, Weiming Zhao, Zhiyou Liu, Jianlin Guo, Cunshuan Xu

Abstract read
PubMed
In one paragraph

Article in Journal of genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cuifang ChangState Key Laboratory Cultivation Base for Cell Differentiation Regulation, Henan Normal University, Xinxiang 453007, People's Republic of China. zhangjihong@xxmu.edu.cn.
Lingling Xi
Jihong Zhang
Weiming Zhao
Zhiyou Liu
Jianlin Guo
Cunshuan Xu
Henan Normal University · CNHenan Provincial People's Hospital · CNXinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To analyse the mechanism of tumourigenic transformation of NIH3T3 cells at the transcriptional level, we used cancerogen 3-methylcholanthrene (3-MCA) and cancerogenic substance phorbol-12-myristate-13-acetate (PMA) to transform NIH3T3 cells and the assessment of transformation was performed using Giemsa staining and methylcellulose colony formation assay. Changes in gene expression profile were detected by Mouse Genome 430 2.0 microarray; and quantitative real-time polymerase chain reaction and Western blotting were used to verify the expression changes of mRNAs and proteins, respectively. With the aid of bioinformatics method, five signalling pathways were identified to participate in different stages of NIH3T3 cell transformation. Further, our study suggested that oncogenes

Indexed as

AnimalsBiomarkers, TumorCell Transformation, NeoplasticCyclin A1Gene Expression ProfilingMiceNIH 3T3 CellsPhosphoprotein PhosphatasesProto-Oncogene Proteins c-junProto-Oncogene Proteins c-mycBiomarkers, TumorCcna1 protein, mouseCyclin A1Myc protein, mousePhosphoprotein PhosphatasesPpm1l protein, mouseProto-Oncogene Proteins c-junProto-Oncogene Proteins c-myc

Identifiers

PMID30555065
OpenAlexW2900191103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.