Evidence map›Paper›PMID 30554917›Full record

ArticleStem cell reports2019

Visualizing the Contribution of Keratin-14

Mijeong Park, Alexander Richardson, Elvis Pandzic, Erwin P Lobo, Renee Whan, Stephanie L Watson, J Guy Lyons, Denis Wakefield, Nick Di Girolamo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
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  8. Review
  9. Article
  10. Optical microsensing reveals spatiotemporal oxygen dynamics in cornea wounds that affect healing via reactive oxygen species.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  11. Article
  12. ACS nano · 2024
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Concise Review: Bioengineering of Limbal Stem Cell Niche.Bioengineering (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Mijeong ParkMechanisms of Disease and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Alexander RichardsonMechanisms of Disease and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Elvis PandzicBiomedical Imaging Facility, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, NSW 2052, Australia.
Erwin P LoboSchool of Mathematics and Statistics, Faculty of Science, University of Sydney, Sydney, NSW 2006, Australia.
Renee WhanBiomedical Imaging Facility, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, NSW 2052, Australia.
Stephanie L WatsonSave Sight Institute, University of Sydney, Sydney, NSW 2006, Australia.
J Guy LyonsDiscipline of Dermatology, Bosch Institute, Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia; Immune Imaging, Centenary Institute, Sydney, NSW 2006, Australia; Cancer Services, Royal Prince Alfred Hospital, Sydney, NSW 2006, Australia.
Denis WakefieldMechanisms of Disease and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Nick Di GirolamoMechanisms of Disease and Translational Research, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address: n.digirolamo@unsw.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is thought that corneal epithelial injuries resolve by leading-edge cells "sliding" or "rolling" into the wound bed. Here, we challenge this notion and show by real-time imaging that corneal wounds initially heal by "basal cell migration." The K14CreER

Indexed as

Wound HealingAdult Stem CellsAnimalsCell MovementCorneal InjuriesEpithelial CellsEpithelium, CornealFemaleKeratin-14Limbus CorneaeMaleMiceMice, Inbred C57BLKeratin-14basal cell migrationcomputational modelingcornea wound healingK14CreER(T2)-Confetti transgenic micelimbal epithelial stem cellsorgan-culture systemspatiotemporal image correlation spectroscopy

Identifiers

PMID30554917
PMCPMC6335450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.