Observational studyJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2018
Cardiovascular magnetic resonance left ventricular strain in end-stage renal disease patients after kidney transplantation.
Observational study in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Reversal of Uraemic Cardiomyopathy following Kidney Transplantation: Systematic Review and Meta-Analysis of Myocardial Strain Compared to Left Ventricular Volumetry as a Potential Early Marker.Kidney & blood pressure research · 2026Pooled it
- Cardiorespiratory fitness and left ventricular recovery after kidney transplantation: evidence, gaps, and future directions.Renal failure · 2026Review
- Left ventricular remodeling and its association with mineral and bone disorder in kidney transplant recipients.Renal failure · 2024Article
- Evaluation of the effect of kidney transplantation on left ventricular myocardial work by noninvasive pressure-strain loops.Frontiers in cardiovascular medicine · 2024Article
- Left atrial and ventricular deformation: alterations and predictive value of echocardiography parameters in end-stage renal disease patients after kidney transplantation.European heart journal. Imaging methods and practice · 2024Article
- Cardiac Magnetic Resonance Imaging in Appraising Myocardial Strain and Biomechanics: A Current Overview.Diagnostics (Basel, Switzerland) · 2023Review
- Experimental renal transplantation in rats improves cardiac dysfunction caused by chronic kidney disease while LVH persists.Frontiers in cardiovascular medicine · 2023Article
- Left ventricular dysfunction with preserved ejection fraction: the most common left ventricular disorder in chronic kidney disease patients.Clinical kidney journal · 2022Review
- Changes in myocardial work associated with pediatric kidney transplantation: A pilot study of short-term postoperative effect.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Cardiac magnetic resonance imaging parameters show association between myocardial abnormalities and severity of chronic kidney disease.Frontiers in cardiovascular medicine · 2022Article
- Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling in mice.Frontiers in cardiovascular medicine · 2022Article
- Artificial Intelligence Algorithm-Based MRI in the Diagnosis of Complications after Renal Transplantation.Contrast media & molecular imaging · 2022Article
- Electrocardiographic parameters of left ventricular hypertrophy and prediction of mortality in hemodialysis patients.Journal of nephrology · 2022Article
- Myocardial strain assessment using cardiovascular magnetic resonance imaging in recipients of implantable cardioverter defibrillators.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Feature-tracking cardiac magnetic resonance left ventricular global longitudinal strain improves 6 months after kidney transplantation associated with reverse remodeling, not myocardial tissue characteristics.The international journal of cardiovascular imaging · 2021Article
- Global longitudinal strain by feature-tracking cardiovascular magnetic resonance imaging predicts mortality in patients with end-stage kidney disease.Clinical kidney journal · 2021Article
- Cardiac MRI assessment of the right ventricle pre-and post-kidney transplant.The international journal of cardiovascular imaging · 2021Article
- The Increase in Paraoxonase 1 Is Associated With Decrease in Left Ventricular Volume in Kidney Transplant Recipients.Frontiers in cardiovascular medicine · 2021Article
- Journal of Cardiovascular Magnetic Resonance: 2017/2018 in review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019Review
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundCardiovascular disease is a significant cause of morbidity and mortality in patients with end-stage renal disease (ESRD) and kidney transplant (KT) patients. Compared with left ventricular (LV) ejection fraction (LVEF), LV strain has emerged as an important marker of LV function as it is less load dependent. We sought to evaluate changes in LV strain using cardiovascular magnetic resonance imaging (CMR) in ESRD patients who received KT, to determine whether KT may improve LV function.
methodsWe conducted a prospective multi-centre longitudinal study of 79 ESRD patients (40 on dialysis, 39 underwent KT). CMR was performed at baseline and at 12 months after KT.
resultsAmong 79 participants (mean age 55 years; 30% women), KT patients had significant improvement in global circumferential strain (GCS) (p = 0.007) and global radial strain (GRS) (p = 0.003), but a decline in global longitudinal strain (GLS) over 12 months (p = 0.026), while no significant change in any LV strain was observed in the ongoing dialysis group. For KT patients, the improvement in LV strain paralleled improvement in LVEF (57.4 ± 6.4% at baseline, 60.6% ± 6.9% at 12 months; p = 0.001). For entire cohort, over 12 months, change in LVEF was significantly correlated with change in GCS (Spearman's r = - 0.42, p < 0.001), GRS (Spearman's r = 0.64, p < 0.001), and GLS (Spearman's r = - 0.34, p = 0.002). Improvements in GCS and GRS over 12 months were significantly correlated with reductions in LV end-diastolic volume index and LV end-systolic volume index (all p < 0.05), but not with change in blood pressure (all p > 0.10).
conclusionsCompared with continuation of dialysis, KT was associated with significant improvements in LV strain metrics of GCS and GRS after 12 months, which did not correlate with blood pressure change. This supports the notion that KT has favorable effects on LV function beyond volume and blood pessure control. Larger studies with longer follow-up are needed to confirm these findings.
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