Evidence map›Paper›PMID 30554563›Full record

ArticleJournal of the American Heart Association2018

Reduced Plasma Kallistatin Is Associated With the Severity of Coronary Artery Disease, and Kallistatin Treatment Attenuates Atherosclerotic Plaque Formation in Mice.

Yuyu Yao, Bing Li, Chang Liu, Cong Fu, Pengfei Li, Youming Guo, Genshan Ma, Naifeng Liu, Lee Chao, Julie Chao

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Clinical Significance of Serum Kallistatin and ENOX1 Levels in Patients with Coronary Heart Disease.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yuyu Yao1 Department of Cardiology Zhongda Hospital Medical School of Southeast University Nanjing China.
Bing Li1 Department of Cardiology Zhongda Hospital Medical School of Southeast University Nanjing China.
Chang Liu1 Department of Cardiology Zhongda Hospital Medical School of Southeast University Nanjing China.
Cong Fu1 Department of Cardiology Zhongda Hospital Medical School of Southeast University Nanjing China.
Pengfei Li2 Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston SC.
Youming Guo2 Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston SC.
Genshan Ma1 Department of Cardiology Zhongda Hospital Medical School of Southeast University Nanjing China.
Naifeng Liu1 Department of Cardiology Zhongda Hospital Medical School of Southeast University Nanjing China.
Lee Chao2 Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston SC.
Julie Chao2 Department of Biochemistry and Molecular Biology Medical University of South Carolina Charleston SC.
Zhongda Hospital Southeast University · CNMedical University of South Carolina · US

Funding

Kallistatin in Vascular InjuryR01HL118516 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CHAO, JULIE · 2014 to 2017
$1.5M
NHLBI NIH HHS R01 HL118516
6 · The paper itself

Abstract

Background Kallistatin exerts beneficial effects on organ injury by inhibiting oxidative stress and inflammation. However, the role of kallistatin in atherosclerosis is largely unknown. Here, we investigated the role and mechanisms of kallistatin in patients with coronary artery disease ( CAD ), atherosclerotic plaques of apoE

Indexed as

AgedAnimalsCoronary Artery DiseaseEndothelium, VascularFemaleHumansMaleMiceMiddle AgedPlaque, AtheroscleroticSerpinsSeverity of Illness IndexkallistatinSerpinsatherosclerosiscoronary artery diseasekallistatinoxidative stresssirtuin 1

Identifiers

PMID30554563
PMCPMC6404169
OpenAlexW2899375556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.