Evidence map›Paper›PMID 30554360›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019

Influence of patient-specific anatomy on medical computed tomography and risk evaluation of minimally invasive surgery at the otobasis.

Vanessa Schieferbein, Judith Bredemann, R Schmitt, I Stenin, T Klenzner, Jörg Schipper, Julia Kristin

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vanessa SchieferbeinDepartment of Otorhinolaryngology, University Hospital Duesseldorf, Duesseldorf, Germany. vanessa.schieferbein@uni-duesseldorf.de.ORCID http://orcid.org/0000-0002-0689-9163
Judith BredemannLaboratory for Machine Tools and Production Engineering WZL, Chair of Production Metrology and Quality Management, RWTH Aachen University, Aachen, Germany.
R SchmittLaboratory for Machine Tools and Production Engineering WZL, Chair of Production Metrology and Quality Management, RWTH Aachen University, Aachen, Germany.
I SteninDepartment of Otorhinolaryngology, University Hospital Duesseldorf, Duesseldorf, Germany.
T KlenznerDepartment of Otorhinolaryngology, University Hospital Duesseldorf, Duesseldorf, Germany.
Jörg SchipperDepartment of Otorhinolaryngology, University Hospital Duesseldorf, Duesseldorf, Germany.
Julia KristinDepartment of Otorhinolaryngology, University Hospital Duesseldorf, Duesseldorf, Germany.

Funding

Deutsche Forschungsgemeinschaft SCHI 310/15-2
6 · The paper itself

Abstract

purposeWith the increasing use of new minimally invasive approaches in temporal bone surgery, the need arises for evaluation of the risk of injury to sensitive anatomical structures. The factors that influence the measurement uncertainty (variation in representation of position and shape of anatomical structures) of imaging are of relevance. We investigate the effect of patients' anatomy on the measurement uncertainty of medical CT.

methodsSix formalin-fixed temporal bones were used, fiducial markers were bone-implanted, and 20 CT scans of each temporal bone were generated. Surgically threatened anatomical structures of importance were defined. Manual segmentation was performed to create 3D surface models, and different Gaussian filters were applied. Analysis points were established along the border of the superior semicircular canal to determine the deviation between the 3D images of the labyrinth. The standard uncertainty was calculated, and one-way analysis of variance was performed (significance level = 5%) to evaluate the effect of certain factors (patient, side, Gaussian filter) on the measurement uncertainty.

resultsThe influence of patient-specific anatomy on the measurement uncertainty of medical CT (p = 0.049) was demonstrated for the first time. The applied Gaussian filter (p = 0.622) and the patient's side (p = 0.341) showed no significant effect.

conclusionThe applied method and the results of the statistical analysis suggest that the patient's individual anatomical conditions affect the measurement uncertainty of medical CT. Thus, the patient's anatomy must be considered as an important influencing factor during risk evaluation concerning minimally invasive and image-guided surgery.

Indexed as

Minimally Invasive Surgical ProceduresPatient SelectionRisk AssessmentTomography, X-Ray ComputedCadaverFiducial MarkersHumansImaging, Three-DimensionalSemicircular CanalsSurgery, Computer-AssistedTemporal BoneVestibule, LabyrinthImage-guided surgeryMeasurement uncertaintyMedical computed tomographyRisk evaluation

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.