Evidence map›Paper›PMID 30554169›Full record

ArticleGenetics2019

Nucleosome Positioning by an Evolutionarily Conserved Chromatin Remodeler Prevents Aberrant DNA Methylation in

Andrew D Klocko, Miki Uesaka, Tereza Ormsby, Michael R Rountree, Elizabeth T Wiles, Keyur K Adhvaryu, Shinji Honda, Eric U Selker

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Remodeling of perturbed chromatin can initiate de novo transcriptional and post-transcriptional silencing.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Histone deacetylation and cytosine methylation compartmentalize heterochromatic regions in the genome organization ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Experimental evidence for the functional importance and adaptive advantage of A-to-I RNA editing in fungi.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Andrew D KlockoInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403 selker@uoregon.edu aklocko@uccs.edu.ORCID 0000-0002-2236-672X
Miki UesakaFaculty of Medical Sciences, University of Fukui, 910-1193, Japan.
Tereza OrmsbyInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.ORCID 0000-0002-2953-9208
Michael R RountreeInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.ORCID 0000-0003-2371-6389
Elizabeth T WilesInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.
Keyur K AdhvaryuInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.
Shinji HondaFaculty of Medical Sciences, University of Fukui, 910-1193, Japan.
Eric U SelkerInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403 selker@uoregon.edu aklocko@uccs.edu.ORCID 0000-0001-6465-0094
University of Oregon · USUniversity of Fukui · JP

Funding

Genetic Aspects of DNA MethylationR37GM035690 · NIGMS · UNIVERSITY OF OREGON · PI SELKER, ERIC U. · 2003 to 2012
$5.2M
GENETIC ASPECTS OF DNA METHYLATIONR01GM035690 · NIGMS · UNIVERSITY OF OREGON · PI SELKER, ERIC U. · 1986 to 2016
$3.3M
Control and function of heterochromatin in Neurospora crassaR35GM127142 · NIGMS · UNIVERSITY OF OREGON · PI SELKER, ERIC U. · 2018 to 2022
$2.6M
Control and Function of Histone H3 Lysine 27 Methylation in NeurosporaR01GM093061 · NIGMS · UNIVERSITY OF OREGON · PI SELKER, ERIC U. · 2012 to 2015
$1.1M
Genetic analysis of DNA methylation in Neurospora crassaF32GM097821 · NIGMS · UNIVERSITY OF OREGON · PI KLOCKO, ANDREW DAVID · 2012 to 2013
$106k
NIGMS NIH HHS F32 GM097821NIGMS NIH HHS R01 GM035690NIGMS NIH HHS R01 GM093061NIGMS NIH HHS R35 GM127142NIGMS NIH HHS R37 GM035690
6 · The paper itself

Abstract

In the filamentous fungus

Indexed as

DNA MethylationChromatinConserved SequenceFungal ProteinsGene Expression Regulation, FungalHistone CodeMethyltransferasesNeurosporaNucleosomesChromatinFungal ProteinsMethyltransferasesNucleosomesCATPDIM-1DNA methylationheterochromatinNeurospora crassanucleosome

Identifiers

PMID30554169
PMCPMC6366918
OpenAlexW2904972799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.