Evidence map›Paper›PMID 30553910›Full record

ArticleDrug and alcohol dependence2019

Shifting characteristics of nonmedical prescription tranquilizer users in the United States, 2005-2014.

Joseph J Palamar, Benjamin H Han, Silvia S Martins

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. [Appropriate Use and Abuse of Sedative-Hypnotic Drugs].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Review
  4. The long-term impact of the earthquake on substance use.International journal of emergency medicine · 2022
    Article
  5. Article
  6. Article
  7. Prescription Drug Misuse: Taking a Lifespan Perspective.Substance abuse : research and treatment · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph J PalamarNew York University Langone Medical Center, Department of Population Health, New York, NY, USA. Electronic address: joseph.palamar@nyulangone.org.
Benjamin H HanNew York University Langone Medical Center, Department of Population Health, New York, NY, USA; New York University School of Medicine, Department of Medicine, Division of Geriatric Medicine and Palliative Care, New York, NY, USA.
Silvia S MartinsColumbia University, Department of Epidemiology, Mailman School of Public Health, New York, NY, USA.

Funding

State medical marijuana laws and NSDUH marijuana use and consequences since 2004R01DA037866 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARTINS, SILVIA SABOIA · 2014 to 2018
$2.3M
Chronic Disease and Health Outcomes of Older Adults with Opioid Use DisordersK23DA043651 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAN, BENJAMIN HYUN · 2018 to 2023
$1.2M
Development of a Rapid Survey to Detect Use of New and Emerging DrugsK01DA038800 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PALAMAR, JOSEPH J · 2015 to 2019
$879k
NIDA NIH HHS K01 DA038800NIDA NIH HHS K23 DA043651NIDA NIH HHS R01 DA037866
6 · The paper itself

Abstract

backgroundBenzodiazepine overdose rates have increased in the US, largely from concomitant use of other drugs such as opioids. Studies are needed to examine trends in prescription tranquilizer (e.g., benzodiazepine) use-with a particular focus on use of other drugs such as opioids-to continue to inform prevention efforts.

methodsWe conducted a secondary analysis of the 2005-2014 National Survey on Drug Use and Health, a repeated cross-sectional, nationally representative probability sample. Trends in past-year nonmedical tranquilizer use and trends in demographic and other past-year substance use characteristics among nonmedical users were examined (N = 560,099).

resultsPrevalence of nonmedical tranquilizer use remained stable from 2005/06 through 2013/14 at 2%. Prevalence of past-year heroin use and heroin use disorder both more than doubled among nonmedical tranquilizer users between 2005/06 and 2013/14 (Ps<.001). Nonmedical opioid use decreased between 2005/06 and 2013/14 (P < .001); however, opioid use disorder increased from 13.4% to 16.7% (P = .019). Prevalence doubled among those age >50 between 2005/06 and 2013/14 from 7.9% to 16.5% (P < .001), and nonmedical tranquilizer use among racial minorities also increased (Ps<.01). Prevalence of nonmedical use also increased among those with health insurance (P = .031), and this increase appeared to be driven by a 190.6% increase in nonmedical use among those with Medicare (from 2.6% to 7.4%; P = .002).

conclusionsCharacteristics of nonmedical tranquilizer users are shifting, and many shifts are related to past-year nonmedical prescription opioid use and heroin use. Prevention needs to be geared in particular towards older individuals and to those who use opioids nonmedically.

Indexed as

AdolescentAdultAnalgesics, OpioidBenzodiazepinesChildCross-Sectional StudiesDrug OverdoseFemaleHumansHypnotics and SedativesMaleMiddle AgedOpioid-Related DisordersPrescriptionsPrevalenceSubstance-Related DisordersAnalgesics, OpioidBenzodiazepinesHypnotics and SedativesTranquilizing AgentsBenzodiazepineGeriatricOpioidTranquilizer

Identifiers

PMID30553910
PMCPMC6359959

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.