Evidence map›Paper›PMID 30553820›Full record

ArticleBiological psychology2019

Interpersonal-level discrimination indices, sociodemographic factors, and telomere length in African-Americans and Whites.

Danielle L Beatty Moody, Daniel K Leibel, Taylor M Darden, Jason J Ashe, Shari R Waldstein, Leslie I Katzel, Hans B Liu, Nan-Ping Weng, Michele K Evans, Alan B Zonderman

Abstract read
In one paragraph

Article in Biological psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Inequities in the Impacts of Hurricanes and Other Extreme Weather Events for Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Review
  5. Geroscience-Centric Perspective for Geriatric Psychiatry: Integrating Aging Biology With Geriatric Mental Health Research.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Diagnosing and Treating Systemic Racism.The New England journal of medicine · 2020
    Article
  16. Racial discrimination and telomere shortening among African Americans: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Danielle L Beatty MoodyDepartment of Psychology, University of Maryland, Baltimore County, Baltimore, MD, USA. Electronic address: dlbeatty@umbc.edu.
Daniel K LeibelDepartment of Psychology, University of Maryland, Baltimore County, Baltimore, MD, USA.
Taylor M DardenDepartment of Psychology, University of Maryland, Baltimore County, Baltimore, MD, USA.
Jason J AsheDepartment of Psychology, University of Maryland, Baltimore County, Baltimore, MD, USA.
Shari R WaldsteinDepartment of Psychology, University of Maryland, Baltimore County, Baltimore, MD, USA; Division of Gerontology and Geriatric Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, Baltimore, MD, USA.
Leslie I KatzelDivision of Gerontology and Geriatric Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, Baltimore, MD, USA.
Hans B LiuDepartment of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Nan-Ping WengLaboratory of Molecular Biology and Immunology, National Institute on Aging, Baltimore, MD, USA.
Michele K EvansLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Baltimore, MD, USA.
Alan B ZondermanLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Baltimore, MD, USA.

Funding

Healthy Aging In Neighborhoods of Diversity Across the Life Span (HANDLS)ZIAAG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2009 to 2025
$70.9M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Behavioral epidemiology of healthy agingZIAAG000199 · NIA · NATIONAL INSTITUTE ON AGING · PI ZONDERMAN, ALAN B · 2013 to 2019
$7.8M
Healthy Aging Neighborhoods of Diversity Across LifespanZ01AG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2001 to 2008
$6.8M
Role of Telomere In Human Lymphocyte Function and AgingZIAAG000756 · NIA · NATIONAL INSTITUTE ON AGING · PI WENG, NAN-PING PETER · 2009 to 2025
$5.5M
HANDLS Scan Substudy: Race, Socioeconomic status, and the BrainR01AG034161 · NIA · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI WALDSTEIN, SHARI · 2009 to 2013
$2.8M
Race, Childhood Social Disadvantage, and the Adult Brain: HANDLS BRAINCHILD.K01AG043581 · NIA · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI BEATTY MOODY, DANIELLE LATHEL · 2014 to 2018
$650k
Intramural NIH HHS Z99 AG999999Intramural NIH HHS ZIA AG000199NIA NIH HHS K01 AG043581NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG034161NIA NIH HHS Z01 AG000513NIGMS NIH HHS R25 GM055036
6 · The paper itself

Abstract

objectiveStudies have linked self-reported discrimination to telomere attrition, a biological marker of accelerated cellular aging. However, it is unknown whether intersections between social categories-race, socioeconomic status (SES), sex, and age-influence the association of varying forms of discrimination with telomere length. We examined these associations in a socioeconomically and racially/ethnically diverse urban sample.

methodsCross-sectional data were from 341 middle-aged (30-64 years) African American and White, community participants in the Healthy Aging in Neighborhoods of Diversity across the Life Span Study (HANDLS). Multiple regression models examined up to 3-way interactions between a discrimination measure (i.e., everyday, racial, gender, lifetime burden, and frequency of discrimination across sources) and two social categories.

resultsAfter adjusting for depressive symptoms, waist circumference, and lifetime substance use, two themes emerged: 1) among women with higher SES, a) greater lifetime discrimination burden (b = -0.23, p =  .011), gender discrimination (b = -0.29, p =  .040), and racial discrimination (b = -0.24, p = 0.023) and 2) among younger adults, irrespective of race and sex, greater frequency of discrimination across sources (b = 0.002, p =  .008) was associated with shorter telomeres.

conclusionsIrrespective of race, women with higher SES and younger adults reporting greater discrimination may be at particular risk for accelerated aging. Telomere attrition promotes and accelerates chronic health conditions for which there are health disparities. Future research explicating intersections among specific discrimination indices and social categories is warranted.

Indexed as

AdultAge FactorsBlack or African AmericanCellular SenescenceCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedRacismRegression AnalysisRisk FactorsSelf ReportSex FactorsSocial ClassAgeDiscriminationRaceSexSocioeconomic statusTelomere attrition

Identifiers

PMID30553820
PMCPMC6438165

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.