ReviewNeuroscience2019
Age-related Changes in Neural Coding of Envelope Cues: Peripheral Declines and Central Compensation.
Review in Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 72 citations in OpenAlex.
- Age-related differences in asymmetric synapses across the central inferior colliculus in the Fischer Brown Norway rat.Aging brain · 2026Article
- Age-related ultrastructural differences in the dorsal cortex of the inferior colliculus in the fischer brown Norway rat.Neurobiology of aging · 2026Article
- Ultrastructural Synaptic Differences in the Central Inferior Colliculus in the 3xTG Mouse Across Three Disease Stages.The Journal of comparative neurology · 2025Article
- Age-related differences in GABAergic synapses across the central inferior colliculus in the Fischer Brown Norway rat.Neurobiology of aging · 2025Article
- Article
- Phenotypic changes of auditory nerve fibers after excitotoxicity.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Sensory representations and pupil-indexed listening effort provide complementary contributions to multi-talker speech intelligibility.Scientific reports · 2024Article
- Rapid and objective assessment of auditory temporal processing using dynamic amplitude-modulated stimuli.Communications biology · 2024Article
- Clinical phenotype and management of sound-induced pain: Insights from adults with pain hyperacusis.medRxiv : the preprint server for health sciences · 2024Article
- Neurometric amplitude modulation detection in the inferior colliculus of Young and Aged rats.Hearing research · 2024Article
- Neural Adaptation at Stimulus Onset and Speed of Neural Processing as Critical Contributors to Speech Comprehension Independent of Hearing Threshold or Age.Journal of clinical medicine · 2024Article
- Neural hyperactivity and altered envelope encoding in the central auditory system: Changes with advanced age and hearing loss.Hearing research · 2024Review
- Rapid and objective assessment of auditory temporal processing using dynamic amplitude-modulated stimuli.bioRxiv : the preprint server for biology · 2024Article
- BOLD fMRI responses to amplitude-modulated sounds across age in adult listeners.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Detecting Central Auditory Processing Disorders in Awake Mice.Brain sciences · 2023Article
- A data-driven approach to identify a rapid screener for auditory processing disorder testing referrals in adults.Scientific reports · 2023Article
- Effects of age on brainstem coding of speech glimpses in interrupted noise.Hearing research · 2023Article
- Inherent envelope fluctuations in forward masking: Effects of age and hearing loss.The Journal of the Acoustical Society of America · 2023Article
- Increased central auditory gain in 5xFAD Alzheimer's disease mice as an early biomarker candidate for Alzheimer's disease diagnosis.Frontiers in neuroscience · 2023Article
- Longitudinal Study of Analgesic Use and Risk of Incident Persistent Tinnitus.Journal of general internal medicine · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Aging listeners often experience difficulties in perceiving temporally complex acoustic cues in noisy environments. These difficulties likely have neurophysiological contributors from various levels of auditory processing. Cochlear synapses between inner hair cells and auditory nerve fibers exhibit a progressive decline with age which is not reflected in the threshold audiogram. The functional consequences of this loss for the coding of suprathreshold sound remain poorly understood. Recent studies suggest that cochlear synaptopathy results in degraded representations of temporal envelope cues at the earliest levels of the auditory pathway. Central nuclei downstream of the auditory nerve exhibit a compensatory plasticity in response to this deafferentation, in the form of altered gain. This results in a modulation frequency selective increase in the representation of envelope cues at the level of the auditory midbrain and cortex. These changes may be shaped by mechanisms such as decreased inhibitory neurotransmission occurring with age across various central auditory nuclei. Altered representations of the differing temporal components of speech due to these interactions between multiple levels of the auditory pathway may contribute to the age-related difficulties hearing speech in noisy environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.