Evidence map›Paper›PMID 30553000›Full record

ArticleThe ocular surface2019

Human meibum chain branching variability with age, gender and meibomian gland dysfunction.

Douglas Borchman, Aparna Ramasubramanian

Abstract read
In one paragraph

Article in The ocular surface, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Meibomian Gland Dysfunction Clinical Practice Guidelines.Japanese journal of ophthalmology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Douglas BorchmanDepartment of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, 40202, USA. Electronic address: Borchman@louisville.edu.
Aparna RamasubramanianDepartment of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, 40202, USA.

Funding

Tear Film Lipid Compositional, Structural, Functional, Relationships, and Dry EyeR01EY026180 · NEI · UNIVERSITY OF LOUISVILLE · PI BORCHMAN, DOUGLAS · 2016 to 2020
$1.4M
NEI NIH HHS R01 EY026180
6 · The paper itself

Abstract

NMR spectroscopy was used to measure hydrocarbon chain branching variability in meibum with age, gender and Meibomian gland dysfuction (MGD). A cohort of 65 meibum donors without dry eye and 31 donors with MGD was studied. Heteronuclear 2D NMR was used to confirm CH

Indexed as

AdolescentAdultAgedAged, 80 and overAgingBiomarkersChildChild, PreschoolFemaleHumansInfantLipid MetabolismLipidsMagnetic Resonance SpectroscopyMaleMeibomian Gland DysfunctionBiomarkersLipidsAgeBranchingDry eyeLipidMeibomian gland dysfunctionMeibumNMR

Identifiers

PMID30553000
PMCPMC6529269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.