Evidence map›Paper›PMID 30552882›Full record

ArticleActa tropica2019

Mechanisms of pyrethroid resistance in Aedes (Stegomyia) aegypti from Colombia.

Angélica Aponte, R Patricia Penilla, Américo D Rodríguez, Clara B Ocampo

Abstract read
In one paragraph

Article in Acta tropica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 58 citations in OpenAlex.

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  15. Worldwide Status of Insecticide Resistance ofJournal of arthropod-borne diseases · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Angélica AponteCentro Internacional de Entrenamiento e Investigaciones Médicas CIDEIM, Carrera 125 N 19-225, Cali, Colombia. Electronic address: aaponte017@gmail.com.
R Patricia PenillaCentro Regional de Investigación en Salud Pública- Instituto Nacional de Salud Pública de México, Avenida 4 Norte 19 calle poniente, CP 307000, Chiapas, Tapachula, Mexico. Electronic address: penilla@insp.mx.
Américo D RodríguezCentro Regional de Investigación en Salud Pública- Instituto Nacional de Salud Pública de México, Avenida 4 Norte 19 calle poniente, CP 307000, Chiapas, Tapachula, Mexico. Electronic address: americo@insp.mx.
Clara B OcampoCentro Internacional de Entrenamiento e Investigaciones Médicas CIDEIM, Carrera 125 N 19-225, Cali, Colombia; Universidad ICESI, Calle 18 N 122-135, Cali, Colombia. Electronic address: claraocampo@cideim.org.co.
Centro Internacional de Entrenamiento e Investigaciones Medicas · COInstituto Nacional de Salud Pública · MX

Funding

Vector/Host-Parasite Interface of Leishmaniasis in ColombiaD43TW006589 · FIC · YALE UNIVERSITY · PI GORE SARAVIA, NANCY, TSCHUDI, CHRISTIAN · 2003 to 2024
$4.3M
FIC NIH HHS D43 TW006589
6 · The paper itself

Abstract

In Colombia Aedes (Stegomyia) aegypti is the main vector of urban arboviruses such as dengue, chikungunya and Zika. This urban mosquito has a well-established capacity to develop insecticide resistance to different types of insecticides (pyrethroids, organochlorides, organophosphates), using multiple resistance mechanisms. An understanding of ongoing resistance mechanisms is critical to determining the activities of vector control programs. In order to identify the biochemical and molecular mechanisms associated with pyrethroid resistance in Colombia, three laboratory-selected strains resistant to DDT, Propoxur and lambdacyhalothrin, and 7 field-collected strains were evaluated. CDC bioassays were performed to measure the susceptibility status to pyrethroid type I (permethrin) and II (deltamethrin and lambdacyhalothrin), and potential cross-resistance to different types of insecticides; organochlorine (DDT), carbamates (propoxur) and organophosphates (malathion). The enzymatic activity of esterases, glutathione S-transferases (GST) and P

Indexed as

Disease VectorsAedesAnimalsColombiaInsecticide ResistanceInsecticidesMosquito VectorsPyrethrinsInsecticidesPyrethrinsAedes aegyptiGlutathion S-transferasesInsecticideskdr mutationsPyrethroidsResistance

Identifiers

PMID30552882
PMCPMC6447284
OpenAlexW2903766557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.