Evidence map›Paper›PMID 30552819›Full record

ArticleHead & neck2019

Masticatory function and related factors after oral oncological treatment: A 5-year prospective study.

Reilly J de Groot, Jan-Willem Wetzels, Matthias A W Merkx, Antoine J W P Rosenberg, Anton F J de Haan, Andries van der Bilt, Jan H Abbink, Caroline M Speksnijder

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Head & neck, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04196127 (Bite Force and Muscle Function in Patients With Tension-type Headache), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04196127 unknown statusnot on this map

Bite Force and Muscle Function in Patients With Tension-type Headache

TypeobservationalSponsorDanish Headache CenterRan2019 to 2021Enrolled100ConditionsHeadache Disorders, Tension-Type HeadacheArmsBite force testing
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Influence of prosthetic rehabilitation on salivary flow, pH, and comfort sensation in patients treated for head and neck cancer.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026
    Article
  3. Article
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  5. Factors influencing objective voice profile and speech intelligibility of patients after oral oncological treatment: a prospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  8. Review
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  15. A retrospective cross-sectional analysis of swallowing and tongue functions in maxillectomy patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  16. Article
  17. Article
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  19. Tongue function and its influence on masticatory performance in patients treated for oral cancer: a five-year prospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reilly J de GrootDepartment of Oral and Maxillofacial Surgery and Special Dental Care, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0003-4837-4389
Jan-Willem WetzelsDepartment of Oral and Maxillofacial Surgery and Special Dental Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Matthias A W MerkxDepartment of Oral and Maxillofacial Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Antoine J W P RosenbergDepartment of Oral and Maxillofacial Surgery and Special Dental Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Anton F J de HaanDepartment for Health Evidence, Section Biostatistics, Radboud University Medical Center, Nijmegen, The Netherlands.
Andries van der BiltDepartment of Oral and Maxillofacial Surgery and Special Dental Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Jan H AbbinkDepartment of Oral and Maxillofacial Surgery and Special Dental Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Caroline M SpeksnijderDepartment of Oral and Maxillofacial Surgery and Special Dental Care, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0003-0540-3741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChewing ability is often compromised in patients with oral cancer. The aim of this study was to identify which factors affect masticatory performance in these patients.

methodsPatients with primary oral cancer were assessed for up to 5 years after primary treatment. Healthy controls were assessed once. A mixed-model analysis was performed, with masticatory performance as outcome measure.

resultsA total of 123 patients were included in the study. Factors positively associated with masticatory performance were number of occlusal units (OU), having functional dentures, and maximum mouth opening (MMO). The impact of tumor location and maximum bite force (MBF) differed per assessment moment. Masticatory performance declined for up to 1 year but recovered at 5 years after treatment.

conclusionMasticatory performance in patients treated for oral cancer is affected by MBF, MMO, number of OU, and dental status. These should be the focus of posttreatment therapy.

Indexed as

AgedCase-Control StudiesDental OcclusionDentition, PermanentDenturesFemaleFollow-Up StudiesHumansMaleMasticationMiddle AgedMouth NeoplasmsProspective StudiesRecovery of Functionbite forcehead and neck neoplasmsmasticationmixed model analysisprospective cohort

Identifiers

PMID30552819
PMCPMC6590803

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.