ArticleDiabetic medicine : a journal of the British Diabetic Association2019
Variability in sleep disturbance, physical activity and quality of life by level of depressive symptoms in women with Type 2 diabetes.
Article in Diabetic medicine : a journal of the British Diabetic Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Associations of food security and food assistance with cardiovascular morbidity and mortality among postmenopausal women from the women's health initiative.Journal of epidemiology and community health · 2026Article
- Association Between Depression and Lung Cancer Risk Among Postmenopausal Women.Cancer medicine · 2025Article
- Pathways From Socioeconomic Factors to Major Cardiovascular Events Among Postmenopausal Veteran and Nonveteran Women: Findings From the Women's Health Initiative.Journal of the American Heart Association · 2024Article
- Relationship of psychotropic medication use with physical function among postmenopausal women.GeroScience · 2024Article
- Article
- Depressive symptoms and antidepressant use in relation to white blood cell count among postmenopausal women from the Women's Health Initiative.Translational psychiatry · 2024Article
- Psychosocial Factors, Stress and Sleep Among Rural Appalachian Kentucky Residents with Type 2 Diabetes Mellitus.Journal of Appalachian health · 2024Article
- Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study.JMIR mental health · 2023Article
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Authors and funding
15 authors.
Funding
Abstract
aimsTo examine (1) the prevalence of depressive symptoms in women with Type 2 diabetes, (2) the associations between depressive symptoms and the following dependent variables: sleep disturbance; physical activity; physical health-related; and global quality of life, and (3) the potential moderating effects of antidepressants and optimism on the relationship between depressive symptoms and dependent variables.
methodsParticipants in the Women's Health Initiative who had Type 2 diabetes and data on depressive symptoms (N=8895) were included in the analyses. In multivariable linear regression models controlling for sociodemographic, medical and psychosocial covariates, we examined the main effect of depressive symptoms, as well as the interactions between depressive symptoms and antidepressant use, and between depressive symptoms and optimism, on sleep disturbance, physical activity, physical health-related quality of life; and global quality of life.
resultsIn all, 16% of women with Type 2 diabetes reported elevated depressive symptoms. In multivariable analyses, women with depressive symptoms had greater sleep disturbance (P<0.0001) and lower global quality of life (P<.0001). We found evidence of significant statistical interaction in the models for quality-of-life outcomes: the increased risk of poor physical health-related quality of life associated with antidepressant use was stronger in women without vs with depressive symptoms, and the association between greater optimism and higher global quality of life was stronger in women with vs without depressive symptoms.
conclusionsTo improve health behaviours and quality of life in women with Type 2 diabetes, sociodemographic and medical characteristics may identify at-risk populations, while psychosocial factors including depression and optimism may be important targets for non-pharmacological intervention.
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