ArticleCerebellum (London, England)2019
What Is Behind Cerebellar Vertigo and Dizziness?
Article in Cerebellum (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- The Spectrum of Peripheral-Vestibular Deficits and Their Change Over Time in CANVAS/RFC1-Related Ataxia Systematic Review and Meta-Analysis of Quantitative Head-Impulse Testing.Cerebellum (London, England) · 2025Pooled it
- Pragmatic open-label clinical trial investigating the treatment effects of Ginkgo biloba extract EGb 761 on patients with vertigo and dizziness of various aetiologies.Frontiers in pharmacology · 2026Trial
- Identifying central positional vertigo to prevent diagnostic pitfalls: A case series and review of literature.Radiology case reports · 2026Article
- [Vertigo and oculomotor disorders: diagnosis, anatomical classification and etiology].Die Ophthalmologie · 2026Review
- [The SCD diagnostic strategy, procedure and pathway for episodic vestibular syndrome].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Review
- Migraine is Related to Multiple Sclerosis Brain Lesions in the Central Pain Network with Several Migraine Phenotypes Exhibiting Different Lesion Patterns.Brain topography · 2026Article
- Novel Clinical Insights From a Swedish RFC1 Spectrum Disorder Cohort.European journal of neurology · 2026Article
- Frequency and Phenotype ofNeurology · 2023Article
- Consensus Paper: Ataxic Gait.Cerebellum (London, England) · 2023Article
- Vestibulo-spatial navigation: pathways and sense of direction.Journal of neurophysiology · 2023Article
- Multimodal Mobility Assessment Predicts Fall Frequency and Severity in Cerebellar Ataxia.Cerebellum (London, England) · 2023Article
- Acute positional vertigo in the emergency department-peripheral vs. central positional nystagmus.Frontiers in neurology · 2023Article
- Central positional nystagmus: an update.Journal of neurology · 2022Review
- Integrated analysis of proteome-wide and transcriptome-wide association studies identified novel genes and chemicals for vertigo.Brain communications · 2022Article
- Episodic Vestibular Syndrome with Hyperventilation-Induced Downbeat Nystagmus.Cerebellum (London, England) · 2021Article
- Genome-Wide Association Study Points New Direction for Downbeat Nystagmus Research.Cerebellum (London, England) · 2020Article
- A Variation in FGF14 Is Associated with Downbeat Nystagmus in a Genome-Wide Association Study.Cerebellum (London, England) · 2020Article
- Review
- Vestibular Disorders.Deutsches Arzteblatt international · 2020Review
- Nystagmus characteristics of healthy controls.Journal of vestibular research : equilibrium & orientation · 2020Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The differential diagnosis of vertigo or dizziness as a result of cerebellar disorders can be difficult as many patients with a cerebellar pathology do not present with the full spectrum of cerebellar signs. The main goal of this study was to describe the typical clinical features of these patients with vertigo or dizziness of a cerebellar origin. We reviewed the medical records of 5400 patients with vertigo and dizziness from our tertiary outpatient clinic for vertigo and balance disorders. In 459 the diagnosis of "cerebellar vertigo or dizziness" was made; 90 patients were excluded from further analysis due to evident structural changes in MRI. Of the remaining 369 patients (67.0 ± 15.1, 54% female, symptom duration until diagnosis 5.5 ± 6.9 years), 81% suffered from persistent vertigo or dizziness, 31% from attacks of vertigo and dizziness and 21% from both. Neuro-ophthalmologically, 95% had saccadic smooth pursuit, 80% gaze-holding deficits, 64% a pathological fixation suppression of the VOR, 24% central fixation nystagmus (in 64% of these cases downbeat nystagmus (DBN)), 23% rebound nystagmus, and an ocular misalignment in 84% in near view and 50% in distance view. Eleven percent had isolated mild to moderate cerebellar ocular motor disturbances without any other typical cerebellar signs. The most common diagnoses were sporadic adult-onset degenerative ataxia in 26%; idiopathic DBN syndrome in 20%; cerebellar ataxia, neuropathy, and vestibular areflexia syndrome in 10%; episodic ataxia type 2 in 7%; and multiple system atrophy cerebellar type in 6%. In posturography, a typical cerebellar 3-Hz sway was found in 16%. The diagnostic key to patients with cerebellar vertigo or dizziness is a careful examination of eye movements since practically all of them have cerebellar ocular disturbances.
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Registered trials
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