Evidence map›Paper›PMID 30552621›Full record

ArticleCellular and molecular neurobiology2019

Molecular Imaging of mGluR5 Availability with [

Lauren Kosten, Steven Deleye, Sigrid Stroobants, Leonie Wyffels, Susana Mingote, Stephen Rayport, Steven Staelens

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. A Review of Molecular Imaging of Glutamate Receptors.Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lauren KostenMolecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Steven DeleyeMolecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Sigrid StroobantsMolecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Leonie WyffelsMolecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
Susana MingoteDepartment of Psychiatry, Columbia University, New York, USA.
Stephen RayportDepartment of Psychiatry, Columbia University, New York, USA.
Steven StaelensMolecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium. steven.staelens@uantwerpen.be.ORCID http://orcid.org/0000-0003-3376-0519
University of Antwerp · BENew York Psychoanalytic Society and Institute · US

Funding

Fonds Wetenschappelijk Onderzoek V4.228.16N
6 · The paper itself

Abstract

Many PET tracers enable determination of fluctuations in neurotransmitter release, yet glutamate specifically can not be visualized in a noninvasive manner. Several studies point to the possibility of visualizing fluctuations in glutamate release by changes in affinity of the mGluR5 radioligand [

Indexed as

Molecular ImagingAnimalsBrainCarbon RadioisotopesGlutaminaseGlutamineHeterozygoteMiceOximesPyridinesReceptor, Metabotropic Glutamate 53-(6-methylpyridin-2-ylethynyl)cyclohex-2-enone-O-methyloximeCarbon-11Carbon RadioisotopesGlutaminaseGlutamineOximesPyridinesReceptor, Metabotropic Glutamate 5GlutamateGlutaminasemGluR5Micro PETWestern blot

Identifiers

PMID30552621
PMCPMC11469798
OpenAlexW2905201322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.