Evidence map›Paper›PMID 30552468›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2019

High tibial osteotomy with modern PEEK implants is safe and leads to lower hardware removal rates when compared to conventional metal fixation: a multi-center comparison study.

Mario Hevesi, Jeffrey A Macalena, Isabella T Wu, Christopher L Camp, Bruce A Levy, Elizabeth A Arendt, Michael J Stuart, Aaron J Krych

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. The Role of Alignment in Treating Meniscus Pathology.Current reviews in musculoskeletal medicine · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Removal Rate of the TomofixRevista brasileira de ortopedia · 2023
    Article
  7. Review
  8. Article
  9. High Tibial Osteotomy for Varus Deformity of the Knee.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2021
    Review
  10. Day-Case Opening Wedge High Tibial Osteotomy With Intraosseous PEEK Implant.Arthroscopy, sports medicine, and rehabilitation · 2020
    Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mario HevesiDepartment of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Ave, Suite R200, Minneapolis, MN, 55454, USA.
Jeffrey A MacalenaDepartment of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Ave, Suite R200, Minneapolis, MN, 55454, USA.
Isabella T WuDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Christopher L CampDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Bruce A LevyDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Elizabeth A ArendtDepartment of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Ave, Suite R200, Minneapolis, MN, 55454, USA.
Michael J StuartDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Aaron J KrychDepartment of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. krych.aaron@mayo.edu.
Mayo Clinic · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVarious implant materials have been used in medial, opening-wedge high tibial osteotomy (HTO) including traditional metal and modern polyetheretherketone (PEEK) implants. The purpose of this study was to compare metal and PEEK implants and determine safety, varus deformity correction, as well as short- to mid-term hardware removal and arthroplasty rates.

methodsHTO performed with metal and PEEK implants were reviewed between 2000 and 2015 at two institutions with a minimum of 2 years follow-up. Postoperative complications, radiographic measures, and osteotomy union were compared between groups using Kruskal-Wallis and Fisher's exact testing. Survival free of hardware removal and arthroplasty was compared between groups using Kaplan-Meier testing. Risk factors for HTO conversion to arthroplasty were examined using Cox proportional hazards regression.

resultsNinety-five HTOs were performed in 90 patients (59 M, 31 F) using 50 metal and 45 PEEK implants. Mean follow-up was 4.2 years (range 2.0-16.5). Two metal and two PEEK HTO patients experienced nonunions, resulting in revision HTO at a mean of 1.0 years postoperatively (range 0.4-1.4 years). Both implant groups demonstrated similar, significant improvements in coronal deformity, with mean angulation improving from 6.0° and 5.4° varus preoperatively to 1.1° and 1.0° valgus postoperatively for the metal (p < 0.01) and PEEK groups (p < 0.01), respectively. 2- and 5-year hardware removal-free survival was 94% and 94% for PEEK, which was significantly superior to 80% and 73% observed for metal (p = 0.02). 2- and 5-year arthroplasty-free survival was similar for the metal (98% and 94%) and PEEK groups (100% and 78%) (n.s.). HTO performed for focal cartilage defects was observed to demonstrate decreased arthroplasty risk (HR 0.36, p = 0.03) when compared to HTO performed for osteoarthritis.

conclusionsBoth metal and PEEK implants were found to be effective in obtaining and maintaining coronal varus deformity correction, with 88% overall arthroplasty-free survival at 5 years. Metal fixation demonstrated a higher rate of hardware removal while HTO performed for medial compartment osteoarthritis predicted conversation to arthroplasty. LEVEL OF EVIDENCE: III.

Indexed as

KetonesPolyethylene GlycolsAdultArthroplasty, Replacement, KneeBenzophenonesDevice RemovalFemaleFollow-Up StudiesForecastingHumansIncidenceMaleOsteoarthritis, KneeOsteotomyPolymersPostoperative ComplicationsBenzophenonesKetonespolyetheretherketonePolyethylene GlycolsPolymersCartilageHigh tibial osteotomyKneePreservationVarus

Identifiers

PMID30552468
OpenAlexW2904565811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.