ArticleJournal of perinatology : official journal of the California Perinatal Association2019
Comparison of macronutrient content in human milk measured by mid-infrared human milk analyzer and reference methods.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Human Milk Macronutrients and Child Growth and Body Composition in the First Two Years: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- Trial
- Article
- Laser-based mid-IR spectroscopy as a rapid analytical technique for the quantification of human milk proteins.Current research in food science · 2026Article
- Article
- Sexual Dimorphism in Preterm Milk: A Step Toward the Individualized Fortification of Mother's Own Milk?Nutrients · 2025Article
- Factors That May Affect Breast Milk Macronutrient and Energy Content: A Critical Review.Nutrients · 2025Review
- Challenges and Opportunities in Quantifying Bioactive Compounds in Human Breastmilk.Biomolecules · 2025Review
- The Refractive Index of Human Milk Serum: Natural Variations and Dependency on Macronutrient Concentrations.Foods (Basel, Switzerland) · 2024Article
- Amino acid requirements of the infant: the amino acid composition of human breast milk.Frontiers in nutrition · 2024Review
- Human Milk Nutrient Composition Data is Critically Lacking in the United States and Canada: Results from a Systematic Scoping Review of 2017-2022.Advances in nutrition (Bethesda, Md.) · 2023Article
- Nutritional composition of human milk and its association with maternal and perinatal factors.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023Article
- Human milk fatty acid composition and its association with maternal blood and adipose tissue fatty acid content in a cohort of women from Europe.European journal of nutrition · 2022Article
- Comparative study of the most commonly used methods for total protein determination in milk of different species and their ultrafiltration products.Frontiers in nutrition · 2022Article
- Using Nature to Nurture: Breast Milk Analysis and Fortification to Improve Growth and Neurodevelopmental Outcomes in Preterm Infants.Nutrients · 2021Review
- Relationship between traditional maternal diet pattern and breastmilk composition of rural lactating women during the first month postpartum in Shigatse, Tibet.Food science & nutrition · 2021Article
- The need to study human milk as a biological system.The American journal of clinical nutrition · 2021Article
- Concentrating human milk: an innovative point-of-care device designed to increase human milk feeding options for preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Effect of Pooling Practices and Time Postpartum of Milk Donations on the Energy, Macronutrient, and Zinc Concentrations of Resultant Donor Human Milk Pools.The Journal of pediatrics · 2019Article
- Longitudinal Analysis of Macronutrient Composition in Preterm and Term Human Milk: A Prospective Cohort Study.Nutrients · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study aims at evaluating mid-infrared human milk analyzer (HMA) accuracy and precision, in human milk (HM). STUDY
designRöse-Gottlieb, high-performance anion exchange chromatography-pulsed amperometric detection (HPAEC-PAD), Kjeldahl and amino acid analysis (AA) were selected as references for total fat, lactose and total protein determination.
resultsNo significant difference was observed in lactose content between HMA and HPAEC-PAD. Significant differences were observed in fat and protein content between HMA and reference methods. However, the difference in fat content was lower than 12%, and therefore within the variability declared by supplier. For protein determination, the BCA protein assay was selected. No significant differences were observed in total protein content measured by BCA assay, Kjeldahl and AA methods.
conclusionsHMA was reliable for the quantification of total fat and lactose content, but not for total protein one. The latter was measured by BCA assay, which yielded comparable results to Kjeldahl and AA methods.
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Registered trials
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