ArticleScientific reports2018
Connectivity of the Superficial Muscles of the Human Perineum: A Diffusion Tensor Imaging-Based Global Tractography Study.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Diffusion tensor imaging of the pelvic floor muscles and pelvic organs: a systematic review.Frontiers in medical technology · 2026Pooled it
- Postpartum perineal pain and its association with sub-classified second-degree tears and perineal trauma-A follow-up of a randomized controlled trial.Acta obstetricia et gynecologica Scandinavica · 2024Trial
- Passive Mechanical Testing of Female Human Levator Ani and Superficial Perineal Muscles.Annals of biomedical engineering · 2026Article
- Near-Infrared Spectroscopy as a Resource for Assessing the Rest and Activation of Pelvic Floor Muscles in Young Adult Women: A Cross-Sectional Study.Journal of biophotonics · 2026Article
- Proof of concept 3D ultrasound strain imaging measuring effect of a ring pessary on avulsed puborectal muscle.Communications medicine · 2025Article
- Contrast-enhanced Micro-CT imaging of a foetal female pelvic floor reveals anatomical details.PloS one · 2025Article
- Novel Application of Photogrammetry to Quantify Fascicle Orientations of Female Cadaveric Pelvic Floor Muscles.Annals of biomedical engineering · 2021Article
- Treatment of Stress Urinary Incontinence with Muscle Stem Cells and Stem Cell Components: Chances, Challenges and Future Prospects.International journal of molecular sciences · 2021Review
- The Value of Brain Resting-State Functional Magnetic Resonance Imaging on Image Registration Algorithm in Analyzing Abnormal Changes of Neuronal Activity in Patients with Type 2 Diabetes.Contrast media & molecular imaging · 2021Article
- Evaluation of Urinary Sphincter Function by Rapid Magnetic Resonance Diffusion Tensor Imaging.International neurourology journal · 2020Article
- Diffusion tensor imaging of the human thigh: consideration of DTI-based fiber tracking stop criteria.Magma (New York, N.Y.) · 2020Article
- Interactive three-dimensional teaching models of the female and male pelvic floor.Clinical anatomy (New York, N.Y.) · 2020Article
- High-resolution 3D tractography of fibrous tissue based on polarization-sensitive optical coherence tomography.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Loop analysis of the anal sphincter complex in fecal incontinent patients using functional luminal imaging probe.American journal of physiology. Gastrointestinal and liver physiology · 2020Article
- Applied Anatomy of Bulbospongiosus Muscle: a Narrative Review.International braz j urol : official journal of the Brazilian Society of UrologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Despite the importance of pelvic floor muscles, significant controversy still exists about the true structural details of these muscles. We provide an objective analysis of the architecture and orientation of the superficial muscles of the perineum using a novel approach. Magnetic Resonance Diffusion Tensor Images (MR-DTI) were acquired in 10 healthy asymptomatic nulliparous women, and 4 healthy males. Global tractography was then used to generate the architecture of the muscles. Micro-CT imaging of a male cadaver was performed for validation of the fiber tracking results. Results show that muscles fibers of the external anal sphincter, from the right and left side, cross midline in the region of the perineal body to continue as transverse perinea and bulbospongiosus muscles of the opposite side. The morphology of the external anal sphincter resembles that of the number '8' or a "purse string". The crossing of muscle fascicles in the perineal body was supported by micro-CT imaging in the male subject. The superficial muscles of the perineum, and external anal sphincter are frequently damaged during child birth related injuries to the pelvic floor; we propose the use of MR-DTI based global tractography as a non-invasive imaging technique to assess damage to these muscles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.