Evidence map›Paper›PMID 30552258›Full record

SynthesisBMJ open2018

Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis.

Ziying Wu, Xiang Ding, Guanghua Lei, Chao Zeng, Jie Wei, Jiatian Li, Hui Li, Tuo Yang, Yang Cui, Yilin Xiong and 2 more

Registry-linked trialOpen access · goldAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05920746 (Type of Magnetic Field and the Effects of Rheumatoid Arthritis Treatment), which is not on this map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05920746 nacompletednot on this mapstarted 2021, after this paper: background citation

Type of Magnetic Field and the Effects of Rheumatoid Arthritis Treatment

TypeinterventionalSponsorJolanta ZwolińskaRan2021 to 2023Enrolled72ConditionsRheumatoid Arthritis, Hand RheumatismArmsKinesiotherapy with magnetotherapy
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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  12. Italian Orthopaedic and Traumatology Society (SIOT) position statement on the non-surgical management of knee osteoarthritis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ziying Wu *Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Xiang Ding *Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Guanghua LeiDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Chao ZengDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Jie WeiDepartment of Health Management Center, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Jiatian LiDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Hui LiDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Tuo YangDepartment of Health Management Center, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Yang CuiInternational Medical Department, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Yilin XiongDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Yilun Wang *Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Dongxing Xie *Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the efficacy and safety of the pulsed electromagnetic field (PEMF) therapy in treating osteoarthritis (OA).

designMeta-analysis. DATA SOURCES: PubMed, Embase, the Cochrane Library and Web of Science were searched through 13 October 2017. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Randomised controlled trials compared the efficacy of PEMF therapy with sham control in patients with OA. DATA EXTRACTION AND SYNTHESIS: Pain, function, adverse effects and characteristics of participants were extracted. RevMan V.5.2 was used to perform statistical analyses.

resultsTwelve trials were included, among which ten trials involved knee OA, two involved cervical OA and one involved hand OA. The PEMF group showed more significant pain alleviation than the sham group in knee OA (standardised mean differences (SMD)=-0.54, 95% CI -1.04 to -0.04, p=0.03) and hand OA (SMD=-2.85, 95% CI -3.65 to -2.04, p<0.00001), but not in cervical OA. Similarly, comparing with the sham-control treatment, significant function improvement was observed in the PEMF group in both knee and hand OA patients (SMD=-0.34, 95% CI -0.53 to -0.14, p=0.0006, and SMD=-1.49, 95% CI -2.12 to -0.86, p<0.00001, respectively), but not in patients with cervical OA. Sensitivity analyses suggested that the exposure duration <=30 min per session exhibited better effects compared with the exposure duration >30 min per session. Three trials reported adverse events, and the combined results showed that there was no significant difference between PEMF and the sham group.

conclusionsPEMF could alleviate pain and improve physical function for patients with knee and hand OA, but not for patients with cervical OA. Meanwhile, a short PEMF treatment duration (within 30 min) may achieve more favourable efficacy. However, given the limited number of study available in hand and cervical OA, the implication of this conclusion should be cautious for hand and cervical OA.

Indexed as

HumansMagnetic Field TherapyOsteoarthritisPatient SafetyRandomized Controlled Trials as TopicTreatment Outcomeeoarthritismeta-analysispulsed electromagnetic fieldrandomized controlled trial

Identifiers

PMID30552258
PMCPMC6303578
OpenAlexW2903626408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.