Evidence map›Paper›PMID 30552187›Full record

ArticleApplied and environmental microbiology2019

A Combination of Linalool, Vitamin C, and Copper Synergistically Triggers Reactive Oxygen Species and DNA Damage and Inhibits

Tamoghna Ghosh, Santosh Kumar Srivastava, Amit Gaurav, Alok Kumar, Piyush Kumar, Ajit Singh Yadav, Ranjana Pathania, Naveen Kumar Navani

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Etrog Citron (Pharmaceutics · 2025
    Review
  3. Monoterpenoid synergy: a new frontier in biological applications.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Antibacterial Mechanism of Linalool againstFoods (Basel, Switzerland) · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Immunomodulatory and Antimicrobial Effects of Vitamin C.European journal of microbiology & immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tamoghna Ghosh *Chemical Biology Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Santosh Kumar Srivastava *Chemical Biology Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Amit GauravMolecular Bacteriology & Chemical Genetics Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Alok KumarChemical Biology Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Piyush KumarChemical Biology Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Ajit Singh YadavPost-Harvest Technology Division, ICAR-Central Avian Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Ranjana PathaniaMolecular Bacteriology & Chemical Genetics Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Naveen Kumar NavaniChemical Biology Laboratory, Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India navnifbs@iitr.ac.in.
Indian Institute of Technology Roorkee · INCentral Avian Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inappropriate and disproportionate use of antibiotics is contributing immensely to the development of antibiotic resistance in bacterial species associated with food contamination. The use of natural products in combination can be a potent alternative hurdle strategy to inactivate foodborne pathogens. Here, we explored the pro-oxidant properties of essential oil

Indexed as

Acyclic MonoterpenesAnti-Bacterial AgentsAscorbic AcidCopperDNA DamageDrug CombinationsDrug SynergismEscherichia coliHumansMicrobial Sensitivity TestsMicrobial ViabilityOils, VolatileReactive Oxygen SpeciesSalmonella entericaVibrioAcyclic MonoterpenesAnti-Bacterial AgentsAscorbic AcidCopperDrug CombinationslinaloolOils, VolatileReactive Oxygen Speciesantimicrobial agentscopperessential oilfoodborne pathogensoxidative stressROSSalmonella enterica subsp. enterica serovar TyphiVibrio fluvialisvitamin C

Identifiers

PMID30552187
PMCPMC6365828
OpenAlexW2903745398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.