Evidence map›Paper›PMID 30552078›Full record

Trial reportJournal of medical Internet research2018

Efficacy of a Parent-Based, Indicated Prevention for Anorexia Nervosa: Randomized Controlled Trial.

Corinna Jacobi, Kristian Hütter, Ulrike Völker, Katharina Möbius, Robert Richter, Mickey Trockel, Megan Jones Bell, James Lock, C Barr Taylor

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  5. Leveraging Technology to Enhance Eating Disorder Treatment Outcomes.The Psychiatric clinics of North America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Corinna JacobiKlinische Psychologie & E-Mental Health, Institut für Klinische Psychologie und Psychotherapie, Universität Dresden, Dresden, Germany.ORCID 0000-0002-0982-0596
Kristian HütterKlinische Psychologie & E-Mental Health, Institut für Klinische Psychologie und Psychotherapie, Universität Dresden, Dresden, Germany.ORCID 0000-0002-1544-4013
Ulrike VölkerKlinik für Psychiatrie und Psychotherapie, Städtisches Klinikum Görlitz, Görlitz, Germany.ORCID 0000-0001-5866-5089
Katharina MöbiusKlinik für Psychosomatische Medizin und Psychotherapie, Städtisches Klinikum Görlitz, Görlitz, Germany.ORCID 0000-0003-4356-7640
Robert RichterSächsische Bildungsagentur, Regionalstelle Leipzig, Leipzig, Germany.ORCID 0000-0003-1750-1533
Mickey TrockelDepartment of Psychiatry, Stanford University School of Medicine, Stanford, CA, United States.ORCID 0000-0001-7191-5791
Megan Jones BellHeadspace, Santa Monica, CA, United States.ORCID 0000-0002-0514-5888
James LockDepartment of Psychiatry, Stanford University School of Medicine, Stanford, CA, United States.ORCID 0000-0002-5169-1484
C Barr TaylorDepartment of Psychiatry, Stanford University School of Medicine, Stanford, CA, United States.ORCID 0000-0002-4564-6548
Stanford University · USKlinikum Görlitz · DEKlinik und Poliklinik für Psychotherapie und Psychosomatik · DEDigitalSpace (United States) · USSaxon Academy of Sciences and Humanities in Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWeb-based preventive interventions can reduce risk and incidence of bulimia and binge eating disorders among young high-risk women. However, their specific effects on core symptoms of anorexia nervosa (AN) are rather weak.

objectiveThe primary objective of this study was to evaluate the efficacy of an indicated, parent-based, Web-based preventive program Eltern als Therapeuten (E@T) in reducing risk factors and symptoms of AN.

methodsGirls aged between 11 and 17 years were screened by selected risk factors and early symptoms of AN. At-risk families were then randomized to E@T or an assessment-only control condition. Assessments took place at pre- and postintervention (6 weeks later) and at 6- and 12-month follow-up (FU).

resultsA total of 12,377 screening questionnaires were handed out in 86 German schools, and 3941 including consent returned. Overall, 477 (447/3941, 12.10%) girls were identified as at risk for AN and 256 of those could be contacted. In all, 66 families (66/256, 25.8% of those contacted) were randomized to the E@T or a wait-list control condition, 43 (43/66, 65%) participated in postassessments, and 27 (27/66, 41%) in 12-month FUs. Due to low participation and high dropout rates of parents, recruitment was terminated prematurely. At 12-month FU, girls' expected body weight (EBW) percentage was significantly greater for intervention participants compared with control participants (group by time interaction beta=21.0 [CI 5.81 to 36.13], P=.007; group by time squared interaction beta=-15.5 [CI -26.6 to -4.49], P=.007; estimated Cohen d=0.42]. No other significant effects were found on risk factors and attitudes of disturbed eating.

conclusionsDespite a significant increase in girls' EBW percentage, parental participation and adherence to the intervention were low. Overall, parent-based, indicated prevention for children at risk for AN does not seem very promising, although it might be useful for parents who engage in the intervention.

trial registrationInternational Standard Randomized Controlled Trial Number (ISRCTN): 18614564; http://www.isrctn.com/ISRCTN18614564 (Archived by WebCite at http://www.webcitation.org/74FTV1EpF).

Indexed as

InternetAdolescentAnorexia NervosaBody WeightChildFemaleHumansParentsRisk Factorsanorexia nervosaindicated preventioninternetparental interventionrandomized controlled trial

Identifiers

PMID30552078
PMCPMC6315221
OpenAlexW2811339320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.