ArticleEnvironment international2019
The association between natural gas well activity and specific congenital anomalies in Oklahoma, 1997-2009.
Article in Environment international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Oil and Gas Development and Adverse Birth Outcomes: A Qualitative and Quantitative Bias Analysis of the Epidemiologic Literature.Current environmental health reports · 2026Pooled it
- The public health impacts of mining in Australia.The Medical journal of Australia · 2025Pooled it
- Structural birth defects and exposure to oil and gas wells during pregnancy.Pediatric research · 2026Article
- Article
- A Narrative Review of Spatial-Temporal Data Sources for Estimating Population-Level Exposures to Oil and Gas Development in the United States.Current environmental health reports · 2025Review
- IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Evidence for reproductive health effects following exposure to hydraulic fracturing chemical mixtures.Reproduction (Cambridge, England) · 2024Review
- Invited Perspective: Drilling Down into the Mechanisms Linking Oil and Gas Development to Adverse Perinatal Health Outcomes.Environmental health perspectives · 2024Article
- The human health effects of unconventional oil and gas development (UOGD): A scoping review of epidemiologic studies.Canadian journal of public health = Revue canadienne de sante publique · 2024Article
- Residential proximity to unconventional oil and gas development and birth defects in Ohio.Environmental research · 2023Article
- Associations between occurrence of birth defects and hydraulic fracturing activities in Barnett shale region, Texas.Heliyon · 2023Article
- Congenital anomalies associated with oil and gas development and resource extraction: a population-based retrospective cohort study in Texas.Journal of exposure science & environmental epidemiology · 2023Article
- Assessing Exposure to Unconventional Oil and Gas Development: Strengths, Challenges, and Implications for Epidemiologic Research.Current environmental health reports · 2022Review
- Maternal proximity to mountain-top removal mining and birth defects in Appalachian Kentucky, 1997-2003.PloS one · 2022Article
- Meta-analyses of maternal exposure to atmospheric particulate matter and risk of congenital anomalies in offspring.Environmental science and pollution research international · 2021Review
- Petro-riskscapes and environmental distress in West Texas: Community perceptions of environmental degradation, threats, and loss.Energy research & social science · 2020Article
- Flaring from Unconventional Oil and Gas Development and Birth Outcomes in the Eagle Ford Shale in South Texas.Environmental health perspectives · 2020Article
- Residential Proximity to Oil and Gas Development and Birth Outcomes in California: A Retrospective Cohort Study of 2006-2015 Births.Environmental health perspectives · 2020Article
- Chemical Exposures, Health, and Environmental Justice in Communities Living on the Fenceline of Industry.Current environmental health reports · 2020Review
- Unconventional natural gas development and adverse birth outcomes in Pennsylvania: The potential mediating role of antenatal anxiety and depression.Environmental research · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundNatural gas drilling may pose multiple health risks, including congenital anomalies, through air pollutant emissions and contaminated water. Two recent studies have evaluated the relationship between natural gas activity and congenital anomalies, with both observing a positive relationship.
objectivesWe aimed to evaluate whether residence near natural gas wells is associated with critical congenital heart defects (CCHD), neural tube defects (NTD), and oral clefts in Oklahoma, the third highest natural gas producing state in the US.
methodsWe conducted a retrospective cohort study among singleton births in Oklahoma (n = 476,600) to evaluate natural gas activity and congenital anomalies. We calculated an inverse distance-squared weighted (IDW) score based on the number of actively producing wells within a two-mile radius of the maternal residence during the month of delivery. We used modified Poisson regression with robust error variance to estimate prevalence proportion ratios (PPR) and 95% confidence intervals (CI) for the association between tertiles of natural gas activity (compared to no wells) and CCHD, NTD, and oral clefts adjusted for maternal education.
resultsWe observed an increased, though imprecise, prevalence of NTDs among children with natural gas activity compared to children with no wells (2nd tertile PPR: 1.34, 95% CI: 0.93, 1.93; 3rd tertile PPR: 1.20, 95% CI: 0.82, 1.75). We observed no association with CCHD or oral clefts overall. Specific CCHDs of common truncus, transposition of the great arteries, pulmonary valve atresia and stenosis, tricuspid valve atresia and stenosis, interrupted aortic arch, and total anomalous pulmonary venous connection were increased among those living in areas with natural gas activity compared to those living in areas without activity, though not statistically significant. DISCUSSION: Our results were similar to previous studies for NTDs and specific CCHDs. Future directions include evaluating the association between specific phases of the drilling process and congenital anomalies to better refine the relevant exposure period.
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