Evidence map›Paper›PMID 30551760›Full record

ReviewCurrent opinion in insect science2018

Reproducibility and relevance in insect-arbovirus infection studies.

Anthony James Wilson, Lara Ellen Harrup

Abstract readReview
In one paragraph

Review in Current opinion in insect science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Viruses · 2024
    Review
  4. Microbiology spectrum · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Evolutionary Ecology ofAnnual review of genetics · 2019
    Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anthony James WilsonThe Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 0NF, United Kingdom. Electronic address: Anthony.wilson@pirbright.ac.uk.
Lara Ellen HarrupThe Pirbright Institute, Ash Road, Pirbright, Woking, Surrey GU24 0NF, United Kingdom.

Funding

Biotechnology and Biological Sciences Research Council BB/M028372/1Biotechnology and Biological Sciences Research Council BB/P016057/1Biotechnology and Biological Sciences Research Council BB/P016472/1Biotechnology and Biological Sciences Research Council BBS/E/I/00007036
6 · The paper itself

Abstract

Experimental infections of insects with arboviruses are performed to achieve a variety of objectives but principally to draw inferences about the potential role of field populations in transmission or to explore the molecular basis of vector-pathogen interactions. The design of such studies determines both their reproducibility and the extent to which their results can be extrapolated to natural environments, and is constrained by the resources available. We discuss recent findings regarding the effects of nutrition, the microbiome, co-infecting agents and feeding methods on the outcome of such experiments, and identify resource-efficient ways to increase their relevance and reproducibility, including the development of community standards for reporting such studies and better standards for cell line and colony authentication.

Indexed as

AnimalsArbovirusesArbovirus InfectionsHost-Pathogen InteractionsInsectaInsect VectorsReproducibility of Results

Identifiers

PMID30551760
PMCPMC6299244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.