Evidence map›Paper›PMID 30551660›Full record

ArticleMarine drugs2018

MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria.

Chi Ying Gary Ding, Li Mei Pang, Zhao-Xun Liang, Kau Kiat Kelvin Goh, Evgenia Glukhov, William H Gerwick, Lik Tong Tan

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Metabolomics on the study of marine organisms.Metabolomics : Official journal of the Metabolomic Society · 2022
    Review
  4. Review
  5. Article
  6. Article
  7. Article
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  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chi Ying Gary DingNatural Sciences and Science Education, National Institute of Education, Nanyang Technological University, Singapore 637616, Singapore. ding_gary@yahoo.com.sg.
Li Mei PangSchool of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore. PANG0165@e.ntu.edu.sg.
Zhao-Xun LiangSchool of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore. ZXLiang@ntu.edu.sg.
Kau Kiat Kelvin GohSingapore Phenome Centre, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singaporekelvin.goh.kau.kiat@sgh.com.sg (K.K.K.G.). Singaporekelvin.goh.kau.kiat@sgh.com.sg.
Evgenia GlukhovCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093, USA. eglukhov@ucsd.edu.
William H GerwickCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093, USA. wgerwick@ucsd.edu.ORCID 0000-0003-1403-4458
Lik Tong TanNatural Sciences and Science Education, National Institute of Education, Nanyang Technological University, Singapore 637616, Singapore. liktong.tan@nie.edu.sg.
Nanyang Technological University · SGScripps Institution of Oceanography · US

Funding

National Research Foundation Singapore MSRDP-P15
6 · The paper itself

Abstract

Certain strains of cyanobacteria produce a wide array of cyanotoxins, such as microcystins, lyngbyatoxins and aplysiatoxins, that are associated with public health issues. In this pilot study, an approach combining LC-MS/MS and molecular networking was employed as a rapid analytical method to detect aplysiatoxins present in four environmental marine cyanobacterial samples collected from intertidal areas in Singapore. Based on 16S-ITS rRNA gene sequences, these filamentous cyanobacterial samples collected from Pulau Hantu were determined as

Indexed as

Aquatic OrganismsChromatography, High Pressure LiquidDNA, BacterialLyngbya ToxinsMolecular ConformationOscillatoriaPilot ProjectsRNA, Ribosomal, 16SSingaporeTandem Mass SpectrometryTrichodesmiumaplysiatoxinDNA, BacterialLyngbya ToxinsRNA, Ribosomal, 16Saplysiatoxinfilamentous marine cyanobacteriamolecular networkingOkeania sp., Oscillatoria spTrichodesmium erythraeum

Identifiers

PMID30551660
PMCPMC6315786
OpenAlexW2904204505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.