Evidence map›Paper›PMID 30551624›Full record

ArticleMolecules (Basel, Switzerland)2018

Evaluation of the Novel Synthetic Tyrosinase Inhibitor (

EunJin Bang, Sang-Gyun Noh, Sugyeong Ha, Hee Jin Jung, Dae Hyun Kim, A Kyoung Lee, Min Kyung Hyun, Dongwan Kang, Sanggwon Lee, Chaeun Park and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecules (Basel, Switzerland) · 2024
    Article
  4. Heterocyclic Compounds as Synthetic Tyrosinase Inhibitors: Recent Advances.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Journal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

EunJin BangCollege of Pharmacy, Pusan National University, Busan 46241, Korea. ejbang@pusan.ac.kr.
Sang-Gyun NohCollege of Pharmacy, Pusan National University, Busan 46241, Korea. rskrsk92@naver.com.
Sugyeong HaCollege of Pharmacy, Pusan National University, Busan 46241, Korea. tnrn34@hanmail.net.
Hee Jin JungCollege of Pharmacy, Pusan National University, Busan 46241, Korea. hjjung2046@pusan.ac.kr.
Dae Hyun KimCollege of Pharmacy, Pusan National University, Busan 46241, Korea. bioimmune@hanmail.net.
A Kyoung LeeCollege of Pharmacy, Pusan National University, Busan 46241, Korea. lak000@naver.com.
Min Kyung HyunCollege of Pharmacy, Pusan National University, Busan 46241, Korea. Mminn94@naver.com.
Dongwan KangCollege of Pharmacy, Pusan National University, Busan 46241, Korea. 3607@pusan.ac.kr.
Sanggwon LeeCollege of Pharmacy, Pusan National University, Busan 46241, Korea. lsk3232@pusan.ac.kr.
Chaeun ParkCollege of Pharmacy, Pusan National University, Busan 46241, Korea. sauryyyy@pusan.ac.kr.
Hyung Ryong MoonCollege of Pharmacy, Pusan National University, Busan 46241, Korea. mhr108@pusan.ac.kr.ORCID 0000-0003-1119-7112
Hae Young ChungCollege of Pharmacy, Pusan National University, Busan 46241, Korea. hyjung@pusan.ac.kr.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tyrosinase is a key enzyme in melanin synthesis, catalyzing the initial rate-limiting steps of melanin synthesis. Abnormal and excessive melanin synthesis is the primary cause of serious skin disorders including melasma, senile lentigo, freckles, and age spots. In attempts to find potent and safe tyrosinase inhibitors, we designed and synthesized a novel compound, (

Indexed as

Computer SimulationAgaricalesAnimalsCell SurvivalChromansDrug DesignEnzyme InhibitorsInhibitory Concentration 50KineticsMelaninsMelanoma, ExperimentalMiceMolecular Docking SimulationMonophenol MonooxygenasePyronesChromansEnzyme Inhibitorskojic acidMelaninsMonophenol MonooxygenasePyronesB16F10in silico docking simulationtyrosinase(Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-oneα-melanocyte-stimulating hormone

Identifiers

PMID30551624
PMCPMC6321646
OpenAlexW2905302899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.