Evidence map›Paper›PMID 30551596›Full record

ArticlePharmaceuticals (Basel, Switzerland)2018

Synthesis and Initial In Vivo Evaluation of [

Sean S Tanzey, Xia Shao, Jenelle Stauff, Janna Arteaga, Phillip Sherman, Peter J H Scott, Andrew V Mossine

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Evaluation of [Molecular imaging and biology · 2025
    Article
  5. Review
  6. Fully automated radiosynthesis of [American journal of nuclear medicine and molecular imaging · 2024
    Article
  7. Automated radiosynthesis of [American journal of nuclear medicine and molecular imaging · 2024
    Article
  8. Review
  9. Development and Optimization ofACS pharmacology & translational science · 2023
    Review
  10. Article
  11. First-in-human use ofEJNMMI research · 2022
    Article
  12. Review
  13. Synthesis and Evaluation of aPharmaceuticals (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Towards PET imaging of the dynamic phenotypes of microglia.Clinical and experimental immunology · 2021
    Review
  16. ACS chemical neuroscience · 2021
    Article
  17. Neuroinflammation PET Imaging: Current Opinion and Future Directions.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sean S TanzeyDepartment of Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. tanzeys@umich.edu.ORCID 0000-0002-7423-6142
Xia ShaoDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109, USA. xshao@umich.edu.
Jenelle StauffDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109, USA. jrstauff@umich.edu.
Janna ArteagaDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109, USA. jannaa@umich.edu.
Phillip ShermanDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109, USA. psherman@umich.edu.
Peter J H ScottDepartment of Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. pjhscott@umich.edu.ORCID 0000-0002-6505-0450
Andrew V MossineDepartment of Radiology, University of Michigan, Ann Arbor, MI 48109, USA. avmossine@gmail.com.ORCID 0000-0001-6289-196X
University of Michigan · US

Funding

University of Michigan College of PharmacyU.S. Department of Energy DE-SC0012484
6 · The paper itself

Abstract

Positron emission tomography (PET) imaging of Colony Stimulating Factor 1 Receptor (CSF1R) is a new strategy for quantifying both neuroinflammation and inflammation in the periphery since CSF1R is expressed on microglia and macrophages. AZ683 has high affinity for CSF1R (K

Indexed as

carbon-11microglianeuroinflammationpositron emission tomographyradiochemistry

Identifiers

PMID30551596
PMCPMC6316681
OpenAlexW2899429372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.