Evidence map›Paper›PMID 30551573›Full record

ArticleMarine drugs2018

Seasonal Variations in the Metabolome and Bioactivity Profile of

Edwin Heavisides, Caroline Rouger, Anna F Reichel, Cornelia Ulrich, Arlette Wenzel-Storjohann, Susanne Sebens, Deniz Tasdemir

Abstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Metabolomic characterization of algal nutraceuticals to elucidate their biological activities.Metabolomics : Official journal of the Metabolomic Society · 2025
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  14. Metabolomics on the study of marine organisms.Metabolomics : Official journal of the Metabolomic Society · 2022
    Review
  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edwin HeavisidesGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany. edheavisides@outlook.com.ORCID 0000-0003-1205-4017
Caroline RougerGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany. caroline.rouger@u-bordeaux.fr.ORCID 0000-0002-6442-6567
Anna F ReichelGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany. reichel-anna@gmx.de.
Cornelia UlrichGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany. cornelia.ulrich@mpimf-heidelberg.mpg.de.
Arlette Wenzel-StorjohannGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany. awenzel-storjohann@geomar.de.
Susanne SebensInstitute for Experimental Cancer Research, Christian-Albrechts-University Kiel (CAU) and University Medical Center Schleswig-Holstein (UKSH) Campus Kiel, Arnold-Heller-Str. 3, Building 17, 24105 Kiel, Germany. susanne.sebens@email.uni-kiel.de.
Deniz TasdemirGEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany. dtasdemir@geomar.de.ORCID 0000-0002-7841-6271

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The metabolism of seaweeds depends on environmental parameters, the availability of nutrients, and biotic/abiotic stresses; therefore, their chemical composition fluctuates throughout the year. This study investigated seasonal variations in the metabolome of the Baltic Sea brown alga

Indexed as

MetabolomeSeasonsA549 CellsAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicBiological ProductsChromatography, High Pressure LiquidDrug Screening Assays, AntitumorFree Radical ScavengersFucusHumansLiquid-Liquid ExtractionMetabolomicsMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsPlant ExtractsAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicBiological ProductsFree Radical ScavengersPlant Extractsbioactivitybladder wrackdefinitive screening designFucus vesiculosusmacroalgapressurised liquid extractionseasonal variationuntargeted metabolomics

Identifiers

PMID30551573
PMCPMC6315544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.