Evidence map›Paper›PMID 30551337›Full record

ArticlePsychiatry research2018

The component structure of the scales for the assessment of positive and negative symptoms in first-episode psychosis and its dependence on variations in analytic methods.

Marc S Tibber, James B Kirkbride, Eileen M Joyce, Stanley Mutsatsa, Isobel Harrison, Thomas R E Barnes, Vyv Huddy

Abstract read
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marc S TibberDepartment of Clinical, Educational and Health Psychology, UCL, London, UK. Electronic address: m.tibber@ucl.ac.uk.
James B KirkbrideDivision of Psychiatry, UCL, London, UK. Electronic address: j.kirkbride@ucl.ac.uk.
Eileen M JoyceUCL Institute of Neurology, London, UK. Electronic address: e.joyce@ucl.ac.uk.
Stanley MutsatsaSchool of Health Sciences, City University, London, UK. Electronic address: stanley.mutsatsa@city.ac.uk.
Isobel HarrisonDivision of Psychiatry, UCL, London, UK. Electronic address: isobel.harrison@ucl.ac.uk.
Thomas R E BarnesCentre for Psychiatry, Imperial College London, UK. Electronic address: t.r.barnes@imperial.ac.uk.
Vyv HuddyClinical Psychology Unit, Department of Psychology, University of Sheffield, UK. Electronic address: v.huddy@sheffield.ac.uk.

Funding

Wellcome TrustWellcome Trust 064607/Z/01/ZWellcome Trust 101272/Z/13/Z
6 · The paper itself

Abstract

A secondary analysis was undertaken on Scales for the Assessment of Positive and Negative Symptoms (SAPS/SANS) data from 345 first-episode psychosis (FEP) patients gathered in the West London FEP study. The purpose of this study was to determine: (i) the component structure of these measures in FEP (primary analyses), and (ii) the dependence of any findings in these primary analyses on variations in analytic methods. Symptom ratings were exposed to data reduction methods and the effects of the following manipulations ascertained: (i) level of analysis (individual symptom vs. global symptom severity ratings), (ii) extraction method (principal component vs. exploratory factor analysis) and (iii) retention method (scree test vs. Kaiser criterion). Whilst global ratings level analysis rendered the classic triad of psychotic syndromes (positive, negative and disorganisation), symptom level analyses revealed a hierarchical structure, with 11 first-order components subsumed by three second-order components, which also mapped on to this syndrome triad. These results were robust across data reduction but not component retention methods, suggesting that discrepancies in the literature regarding the component structure of the SAPS/SANS partly reflect the level of analysis and component retention method used. Further, they support a hierarchical symptom model, the implications of which are discussed.

Indexed as

AdolescentAdultFactor Analysis, StatisticalFemaleHumansLondonMaleMiddle AgedPsychiatric Status Rating ScalesPsychometricsPsychotic DisordersSymptom AssessmentSyndromeYoung AdultDisorganisation symptomsFactor analysisFactor structureNegative symptomsPositive symptomsPsychosis

Identifiers

PMID30551337
PMCPMC6299359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.