Evidence map›Paper›PMID 30550600›Full record

ArticlePloS one2018

Sentinel hospital-based surveillance for norovirus infection in children with gastroenteritis between 2015 and 2016 in Italy.

Simona De Grazia, Gianvito Lanave, Giovanni Maurizio Giammanco, Maria Cristina Medici, Flora De Conto, Fabio Tummolo, Adriana Calderaro, Floriana Bonura, Noemi Urone, Anna Morea and 6 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Bibliometric Analysis of the Literature on Norovirus Disease from 1991-2021.International journal of environmental research and public health · 2022
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Simona De GraziaDipartimento di Scienze per la Promozione della Salute e Materno Infantile "G. D'Alessandro", Università di Palermo, Palermo, Italy.
Gianvito LanaveDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, Valenzano, Italy.
Giovanni Maurizio GiammancoDipartimento di Scienze per la Promozione della Salute e Materno Infantile "G. D'Alessandro", Università di Palermo, Palermo, Italy.
Maria Cristina MediciDipartimento di Medicina e Chirurgia, Università degli Studi di Parma, Parma, Italy.
Flora De ContoDipartimento di Medicina e Chirurgia, Università degli Studi di Parma, Parma, Italy.
Fabio TummoloDipartimento di Medicina e Chirurgia, Università degli Studi di Parma, Parma, Italy.ORCID 0000-0002-1059-6894
Adriana CalderaroDipartimento di Medicina e Chirurgia, Università degli Studi di Parma, Parma, Italy.
Floriana BonuraDipartimento di Scienze per la Promozione della Salute e Materno Infantile "G. D'Alessandro", Università di Palermo, Palermo, Italy.
Noemi UroneDipartimento di Scienze per la Promozione della Salute e Materno Infantile "G. D'Alessandro", Università di Palermo, Palermo, Italy.
Anna MoreaDipartimento di Scienze Biomediche e Oncologia Umana, Università Aldo Moro di Bari, Bari, Italy.
Daniela LoconsoleDipartimento di Scienze Biomediche e Oncologia Umana, Università Aldo Moro di Bari, Bari, Italy.ORCID 0000-0003-2057-9745
Cristiana CatellaDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, Valenzano, Italy.
Mariarosaria MarinaroDipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Rome, Italy.
Antonio ParisiIstituto Zooprofilattico Sperimentale di Puglia e Basilicata, Foggia, Italy.
Vito MartellaDipartimento di Medicina Veterinaria, Università Aldo Moro di Bari, Valenzano, Italy.ORCID 0000-0002-5740-6947
Maria ChironnaDipartimento di Scienze Biomediche e Oncologia Umana, Università Aldo Moro di Bari, Bari, Italy.ORCID 0000-0002-1043-1256
University of Bari Aldo Moro · ITUniversity of Palermo · ITUniversity of Parma · ITIstituto Superiore di Sanità · ITIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noroviruses are one of the leading causes of gastro-enteric diseases worldwide in all age groups. Novel epidemic noroviruses with GII.P16 polymerase and GII.2 or GII.4 capsid type have emerged worldwide in late 2015 and in 2016. We performed a molecular epidemiological study of the noroviruses circulating in Italy to investigate the emergence of new norovirus strains. Sentinel hospital-based surveillance, in three different Italian regions, revealed increased prevalence of norovirus infection in children (<15 years) in 2016 (14.4% versus 9.8% in 2015) and the emergence of GII.P16 strains in late 2016, which accounted for 23.0% of norovirus infections. The majority of the strains with a GII.P16 polymerase showed a GII.2 capsid genotype (79.5%). Also, a marked circulation of strains with a GII.17 capsid (14.0%) was observed, chiefly in early 2016. The emergence and global spread of non-GII.4 noroviruses pose challenges for the development of vaccine strategies.

Indexed as

Sentinel SurveillanceCaliciviridae InfectionsCapsid ProteinsChildChild, PreschoolGastroenteritisGenetic VariationGenotypeHumansItalyNorovirusPrevalenceRNA-Dependent RNA PolymeraseRNA, ViralSequence Analysis, RNACapsid ProteinsRNA-Dependent RNA PolymeraseRNA, Viral

Identifiers

PMID30550600
PMCPMC6294371
OpenAlexW2905525951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.