Evidence map›Paper›PMID 30550514›Full record

ArticleMedicine and science in sports and exercise2019

Acute Effects of Exercise Intensity on Insulin Sensitivity under Energy Balance.

Gordon Fisher, Barbara A Gower, Fernando Ovalle, Christian E Behrens, Gary R Hunter

Open access · greenAbstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gordon FisherDepartment of Human Studies, University of Alabama at Birmingham, Birmingham, AL.
Barbara A GowerDepartment of Nutrition Science, University of Alabama at Birmingham, Birmingham, AL.
Fernando OvalleDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Christian E BehrensDepartment of Nutrition Science, University of Alabama at Birmingham, Birmingham, AL.
Gary R HunterDepartment of Human Studies, University of Alabama at Birmingham, Birmingham, AL.
University of Alabama at Birmingham · US

Funding

National Dissemination of I-Corps@NCATS: Accelerating Translation through CommercializationUL1TR003096 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M, KIMBERLY, ROBERT P. · 2019 to 2023
$43.6M
Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
Zevalin Radioimmunotherapy Using a Modified TreatmentM01RR000032 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RICH, ROBERT R. · 1985 to 2008
$23.6M
UAB CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE (CCTS) UL1: BPCAUL1RR025777 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUAY-WOODFORD, LISA MARIE · 2008 to 2011
$22.3M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
UAB Diabetes Research and Training CenterP60DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GARVEY, W TIMOTHY · 2008 to 2012
$8.4M
UAB Pre-Doctoral Training Program in Obesity-Related ResearchT32HL105349 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2010 to 2026
$5.7M
EXERCISE TRAINING IN OBESITY-PRONE BLACK AND WHITE WOMENR01DK049779 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOWER, BARBARA A, HUNTER, GARY R · 1995 to 2013
$4.4M
UAB Center for Clinical and Translational Science (CCTS) KL2 ComponentKL2RR025776 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2008 to 2011
$1.3M
NCATS NIH HHS UL1 TR001417NCATS NIH HHS UL1 TR003096NCRR NIH HHS KL2 RR025776NCRR NIH HHS M01 RR000032NCRR NIH HHS UL1 RR025777NHLBI NIH HHS T32 HL105349NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626NIDDK NIH HHS P60 DK079626NIDDK NIH HHS R01 DK049779
6 · The paper itself

Abstract

Exercise is known to improve insulin sensitivity (SI); however, studies to date have been confounded by negative energy deficits after exercise. PURPOSE: The primary objective of this study was to assess the effect of 8 to 16 wk of aerobic exercise training on the SI of untrained women under rigorously controlled energy-balanced conditions. The secondary objective was to determine if one acute bout of moderate-intensity continuous (MIC) or high-intensity interval (HII) exercise further affected SI.

methodsInsulin sensitivity was assessed in 28 untrained women at baseline, after 8 to 16 wk of training with no-exercise (NE) before assessment, 22 h after MIC (50% V˙O2peak), and 22 h after HII (84% V˙O2peak) using a hyperinsulinemic-euglycemic clamp. Participants were in a whole-room indirect calorimeter during each condition, and food intake was adjusted to ensure energy balance across 23 h before each clamp.

resultsThere were no significant differences in acute energy balance between each condition. Results indicated a significant main effect of time, such that SI was higher during the HII condition compared with both baseline and NE (P < 0.05). No significant differences in SI were observed after NE or MIC.

conclusionsWidely reported improvements in SI in response to chronic exercise training may be mediated in part by shifts in energy balance. However, an acute bout of HII exercise may increase SI even in the context of energy balance.

Indexed as

Energy MetabolismExerciseHigh-Intensity Interval TrainingInsulin ResistanceAdultCalorimetry, IndirectFemaleHumansOxygen Consumption

Identifiers

PMID30550514
PMCPMC6465116
OpenAlexW2905171877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.