Evidence map›Paper›PMID 30550487›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2019

Individual and Sexual Network Predictors of HIV Incidence Among Men Who Have Sex With Men in Nigeria.

Rebecca G Nowak, Andrew Mitchell, Trevor A Crowell, Hongjie Liu, Sosthenes Ketende, Habib O Ramadhani, Nicaise Ndembi, Sylvia Adebajo, Julie Ake, Nelson L Michael and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  7. Mpox: an old disease poses a new threat.Bulletin of the World Health Organization · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Rebecca G NowakDivision of Epidemiology and Prevention, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD.
Andrew MitchellDivision of Epidemiology and Prevention, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD.
Trevor A CrowellU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD.
Hongjie LiuDepartment of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park, MD.
Sosthenes KetendeDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Habib O RamadhaniDivision of Epidemiology and Prevention, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD.
Nicaise NdembiInstitute of Human Virology Nigeria, Abuja, Nigeria.
Sylvia AdebajoPopulation Council Nigeria, Abuja, Nigeria.
Julie AkeU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD.
Nelson L MichaelU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD.
William A BlattnerDivision of Epidemiology and Prevention, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD.
Stefan D BaralDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Manhattan E CharuratDivision of Epidemiology and Prevention, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD.
Prevention Institute · USJohns Hopkins University · USUniversity of Maryland, Baltimore · USWalter Reed Army Institute of Research · USHenry M. Jackson Foundation · USInstitute of Human Virology · NGMedical Laboratory Science Council of Nigeria · NGUniversity of Maryland, College Park · US

Funding

Validation of Stigma Metrics for Marginalized Men R01MH110358 · NIMH · JOHNS HOPKINS UNIVERSITY · PI BARAL, STEFAN DAVID · 2017 to 2021
$3.6M
Building TRUSTR01AI120913 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E · 2015 to 2019
$3.3M
TRUSTR01MH099001 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E · 2012 to 2014
$2.9M
Epidemiology Research Training for Public Health Impact in Nigeria (Epi-Nigeria)D43TW010051 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI ABIMIKU, ALASH'LE G., CHARURAT, MANHATTAN E · 2016 to 2020
$1.5M
Role of anal microbiota, local cytokines and HIV in persistence of high-risk human papillomavirusK07CA225403 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI NOWAK, REBECCA G. · 2018 to 2022
$677k
FIC NIH HHS D43 TW010051NCI NIH HHS K07 CA225403NIAID NIH HHS R01 AI120913NIMH NIH HHS R01 MH099001NIMH NIH HHS R01 MH110358PEPFAR
6 · The paper itself

Abstract

backgroundTo date, HIV incidence studies among men who have sex with men (MSM) across sub-Saharan Africa have focused on studying sexual risk practices with less focus on sexual networks.

settingTRUST/RV368 conducted in Abuja and Lagos, Nigeria, recruited MSM using respondent-driven sampling and followed HIV-negative men for incident infection over 4 years.

methodsFour-hundred forty-one HIV-uninfected MSM underwent a parallel rapid HIV testing algorithm every 3 months for up to 18 months. HIV incidence per 100 person-years (PY) and 95% confidence intervals (CIs) were estimated using Poisson regression. Individual and network characteristics were examined using multivariable Cox-proportional hazards regression adjusted and unadjusted for respondent-driven sampling weights.

resultsAmong cohort members with a median age of 23 years [interquartile range (IQR): 20-27], 81 HIV infections occurred over 527 PY (incidence 15.4/100 PY; 95% CI: 12.3 to 19.0). The incidence rate was highest among 16-19 year olds as compared to those 25 years or older (30.9/100 PY; 95% CI: 22.1 to 45.3 vs. 6.9/100 PY; 95% CI: 4.2 to 10.9, respectively). Individual determinants included receptive partnerships, condomless sex, no history of testing for HIV, and rectal gonorrhea. Sexual networks were larger and consisted of an older sexual partner, although there was no clustering by recruitment networks.

conclusionsThese HIV incidence data reinforce the unmet HIV prevention needs among young MSM in Nigeria. Even in the context of emerging HIV diagnostic and prevention strategies, structural challenges including stigma and criminalization of same-sex practices highlight the need for novel implementation approaches in the context of MSM-friendly services.

Indexed as

AdolescentAdultEgocentrismGonorrheaHIV InfectionsHomosexuality, MaleHumansIncidenceMaleMass ScreeningNigeriaProspective StudiesRisk FactorsSexual PartnersSocial StigmaUnsafe Sex

Identifiers

PMID30550487
PMCPMC6519125
OpenAlexW2904021696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.