Evidence map›Paper›PMID 30549495›Full record

ReviewThe Journal of clinical psychiatry2018

What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics.

John I Nurnberger, Jehannine Austin, Wade H Berrettini, Aaron D Besterman, Lynn E DeLisi, Dorothy E Grice, James L Kennedy, Daniel Moreno-De-Luca, James B Potash, David A Ross and 2 more

Abstract readReview
In one paragraph

Review in The Journal of clinical psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Deletion of theFrontiers in pharmacology · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Genetic Advances in Autism.Journal of autism and developmental disorders · 2021
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. The Care of Patients With Complex Mood Disorders.Focus (American Psychiatric Publishing) · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

John I Nurnberger320 W 15th St, Indianapolis, IN 46202. jnurnber@iupui.edu.
Jehannine AustinUniversity of British Columbia, Vancouver, British Columbia, Canada.
Wade H BerrettiniUniversity of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Aaron D BestermanUniversity of California Los Angeles Semel Institute of Neuroscience and Human Behavior, Los Angeles, California, USA.
Lynn E DeLisiVA Boston Healthcare System and Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Dorothy E GriceMt Sinai School of Medicine, New York, New York, USA.
James L KennedyCentre for Addiction and Mental Health and University of Toronto, Toronto, Ontario, Canada.
Daniel Moreno-De-LucaWarren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
James B PotashJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.
David A RossYale University School of Medicine, Hartford, Connecticut, USA.
Thomas G SchulzeInstitute of Psychiatric Phenomics and Genomics, University Hospital, LMU Munich, Munich, Germany.
Gwyneth ZaiCentre for Addiction and Mental Health and University of Toronto, Toronto, Ontario, Canada.

Funding

PRIMING THE PUMP: TRAINING PHYSICIAN-SCIENTISTS IN TRANSLATIONAL PSYCHIATRYR25MH086466 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Melissa Arbuckle, Eduardo David Leonardo · 2009 to 2026
$4.3M
Promoting Research Training During Psychiatry ResidencyR25MH101076 · NIMH · BROWN UNIVERSITY · PI AUDREY TYRKA · 2013 to 2026
$2.8M
NIMH NIH HHS R25 MH086466NIMH NIH HHS R25 MH101076
6 · The paper itself

Abstract

The International Society of Psychiatric Genetics (ISPG) created a Residency Education Committee with the purpose of identifying key genetic knowledge that should be taught in psychiatric training programs. Thirteen committee members were appointed by the ISPG Board of Directors, based on varied training, expertise, gender, and national origin. The Committee has met quarterly for the past 2 years, with periodic reports to the Board and to the members of the Society. The information summarized includes the existing literature in the field of psychiatric genetics and the output of ongoing large genomics consortia. An outline of clinically relevant areas of genetic knowledge was developed, circulated, and approved. This document was expanded and annotated with appropriate references, and the manuscript was developed. Specific information regarding the contribution of common and rare genetic variants to major psychiatric disorders and treatment response is now available. Current challenges include the following: (1) Genetic testing is recommended in the evaluation of autism and intellectual disability, but its use is limited in current clinical practice. (2) Commercial pharmacogenomic testing is widely available, but its utility has not yet been clearly established. (3) Other methods, such as whole exome and whole genome sequencing, will soon be clinically applicable. The need for informed genetic counseling in psychiatry is greater than ever before, knowledge in the field is rapidly growing, and genetic education should become an integral part of psychiatric training.

Indexed as

GeneticsHumansInternship and ResidencyMental DisordersPsychiatryPsychotropic DrugsSocieties, MedicalPsychotropic Drugs

Identifiers

PMID30549495
PMCPMC6480395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.