Evidence map›Paper›PMID 30549000›Full record

ArticleBiometrics2019

Drawing inferences for high-dimensional linear models: A selection-assisted partial regression and smoothing approach.

Zhe Fei, Ji Zhu, Moulinath Banerjee, Yi Li

Abstract read
In one paragraph

Article in Biometrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Debiased lasso after sample splitting for estimation and inference in high-dimensional generalized linear models.The Canadian journal of statistics = Revue canadienne de statistique · 2025
    Article
  3. High-Dimensional Survival Analysis: Methods and Applications.Annual review of statistics and its application · 2023
    Article
  4. Inference for High-Dimensional Censored Quantile Regression.Journal of the American Statistical Association · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhe FeiDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan.
Ji ZhuDepartment of Statistics, University of Michigan, Ann Arbor, Michigan.
Moulinath BanerjeeDepartment of Statistics, University of Michigan, Ann Arbor, Michigan.
Yi LiDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-1720-2760

Funding

The HSPH Education and Research Center of Occupational Safety and HealthT42OH008416 · OH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI CHRISTIANI, DAVID C · 2005 to 2025
$30.5M
The Boston Lung Cancer Survival CohortU01CA209414 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI David C Christiani · 2017 to 2026
$12.2M
Cutting Edge Survival Methods for Epidemiological DataR01AG056764 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI NAN, BIN · 2018 to 2021
$1.3M
NCI NIH HHS U01 CA209414NIA NIH HHS R01 AG056764NIOSH CDC HHS T42 OH008416
6 · The paper itself

Abstract

Drawing inferences for high-dimensional models is challenging as regular asymptotic theories are not applicable. This article proposes a new framework of simultaneous estimation and inferences for high-dimensional linear models. By smoothing over partial regression estimates based on a given variable selection scheme, we reduce the problem to low-dimensional least squares estimations. The procedure, termed as Selection-assisted Partial Regression and Smoothing (SPARES), utilizes data splitting along with variable selection and partial regression. We show that the SPARES estimator is asymptotically unbiased and normal, and derive its variance via a nonparametric delta method. The utility of the procedure is evaluated under various simulation scenarios and via comparisons with the de-biased LASSO estimators, a major competitor. We apply the method to analyze two genomic datasets and obtain biologically meaningful results.

Indexed as

Linear ModelsComputer SimulationGenomicsHumansLeast-Squares AnalysisRegression Analysisconfidence intervalshigh-dimensional inferencehypothesis testingmultisample-splittingSelection-assisted Partial Regression and Smoothing (SPARES)

Identifiers

PMID30549000
PMCPMC6570588

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.