Evidence map›Paper›PMID 30548771›Full record

ReviewGenesis (New York, N.Y. : 2000)2019

Cellular organization and boundary formation in craniofacial development.

Abigail A Kindberg, Jeffrey O Bush

Abstract readReview
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Frontiers in cell and developmental biology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abigail A KindbergDepartment of Cell and Tissue Biology, Program in Craniofacial Biology, and Institute of Human Genetics, University of California at San Francisco, San Francisco, California.
Jeffrey O BushDepartment of Cell and Tissue Biology, Program in Craniofacial Biology, and Institute of Human Genetics, University of California at San Francisco, San Francisco, California.ORCID 0000-0002-6053-8756

Funding

Mechanisms of Eph/Ephrin signaling in craniofacial morphogenesis and craniofrontonasal syndromeR01DE023337 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUSH, JEFFREY OHMANN · 2013 to 2021
$4.3M
Cellular mechanisms of lip and palate fusionR01DE025877 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUSH, JEFFREY OHMANN · 2016 to 2020
$2.0M
A human iPSC-based model of craniofrontonasal syndromeR21DE025923 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUSH, JEFFREY OHMANN · 2017 to 2018
$436k
NIDCR NIH HHS R01 DE023337NIDCR NIH HHS R01 DE025877NIDCR NIH HHS R21 DE025923
6 · The paper itself

Abstract

Craniofacial morphogenesis is a highly dynamic process that requires changes in the behaviors and physical properties of cells in order to achieve the proper organization of different craniofacial structures. Boundary formation is a critical process in cellular organization, patterning, and ultimately tissue separation. There are several recurring cellular mechanisms through which boundary formation and cellular organization occur including, transcriptional patterning, cell segregation, cell adhesion and migratory guidance. Disruption of normal boundary formation has dramatic morphological consequences, and can result in human craniofacial congenital anomalies. In this review we discuss boundary formation during craniofacial development, specifically focusing on the cellular behaviors and mechanisms underlying the self-organizing properties that are critical for craniofacial morphogenesis.

Indexed as

MorphogenesisAnimalsCell DifferentiationHumansNeural CrestSkullboundarycadherincell migrationcell sortingCraniofacialEphephrinneural crestrhombomere

Identifiers

PMID30548771
PMCPMC6503678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.