Evidence map›Paper›PMID 30548453›Full record

ArticleJournal of the American Geriatrics Society2019

Symptom Burden Among Community-Dwelling Older Adults in the United States.

Kushang V Patel, Jack M Guralnik, Elizabeth A Phelan, Nancy M Gell, Robert B Wallace, Mark D Sullivan, Dennis C Turk

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
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  7. Review
  8. Applying natural language processing to understand symptoms among older adult home healthcare patients with urinary incontinence.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2025
    Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Feasibility of a Smartwatch Platform to Assess Ecological Mobility: Real-Time Online Assessment and Mobility Monitor.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Kushang V PatelDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington.ORCID 0000-0002-8443-2876
Jack M GuralnikDepartment of Epidemiology and Public Health, University of Maryland, Baltimore, Maryland.
Elizabeth A PhelanDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington.
Nancy M GellDepartment of Rehabilitation and Movement Science, University of Vermont, Burlington, Vermont.ORCID 0000-0002-3172-8040
Robert B WallaceDepartments of Epidemiology and Internal Medicine, University of Iowa, Iowa City, Iowa.
Mark D SullivanDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington.
Dennis C TurkDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington.

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
NIA NIH HHS U01 AG032947
6 · The paper itself

Abstract

objectivesTo determine the prevalence and impact of common co-occurring symptoms among community-dwelling older adults in the United States.

designThe National Health and Aging Trends Study is a nationally representative, prospective study with annual data collection between 2011 and 2017.

settingCommunity-based, in-person interviews (survey response rates, 71%-96%).

participantsA total of 7,609 community-dwelling Medicare beneficiaries, 65 years or older. MEASUREMENTS: Symptoms assessed at baseline include pain, fatigue, breathing difficulty, sleeping difficulty, depressed mood, and anxiety. Total symptom count ranged from zero to six. Several outcomes were examined, including grip strength, gait speed, and overall lower-extremity function as well as incidence of recurrent falls (two or more per year), hospitalization, disability, nursing home admission, and mortality.

resultsPrevalence of zero, one, two, three, and four or more symptoms was 25.0%, 26.6%, 20.7%, 14.0%, and 13.6%, respectively. Symptom count increased with advancing age and was higher in women than in men. Pain and fatigue were the most common co-occurring symptoms. Higher symptom count was associated with decreased physical capacity. For example, participants with one, two, three, and four or more symptoms had gait speeds that were 0.04, 0.06, 0.09, and 0.13 m/s slower, respectively, than those with no symptoms, adjusting for specific diseases, total number of diseases, and other potential confounders (P < .001). The risk of several adverse outcomes also increased with greater symptom count. For example, compared with those with no symptoms, the adjusted risk ratios for recurrent falls were 1.48 (95% confidence interval [CI] = 1.30-1.70), 1.54 (95% CI = 1.32-1.80), 1.90 (95% CI = 1.55-2.32), and 2.38 (95% CI = 2.00-2.83) for older adults with one, two, three, and four or more symptoms, respectively.

conclusionsSymptoms frequently co-occur among community-dwelling older adults and are strongly associated with increased risk of a range of adverse outcomes. Symptoms represent a potential treatment target for improving outcomes and should be systematically captured in health records. J Am Geriatr Soc 67:223-231, 2019.

Indexed as

ComorbidityAccidental FallsAgedAged, 80 and overAge FactorsFemaleHospitalizationHumansIncidenceIndependent LivingMaleMedicarePrevalenceProspective StudiesSymptom AssessmentUnited Statesdisabilityfallshospitalizationmultimorbiditysymptom burden

Identifiers

PMID30548453
PMCPMC6367017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.