Evidence map›Paper›PMID 30548310›Full record

ArticleJournal of veterinary internal medicine2019

Computed tomographic angiography and ultrasonography in the diagnosis and evaluation of acute pancreatitis in dogs.

John M French, David C Twedt, Sangeeta Rao, Angela J Marolf

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

  1. Serum αVeterinary sciences · 2023
    Article
  2. Imaging techniques in veterinary medicineEuropean journal of radiology open · 2023
    Review
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  6. Advances in the diagnosis of acute pancreatitis in dogs.Journal of veterinary internal medicine · 2021
    Review
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  18. TMAO promotes apoptosis and oxidative stress of pancreatic acinar cells by mediating IRE1α-XBP-1 pathway.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

John M FrenchDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado.ORCID https://orcid.org/0000-0001-8619-9636
David C TwedtDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado.
Sangeeta RaoDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado.
Angela J MarolfDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado.
Colorado State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute pancreatitis in dogs is an under-diagnosed disease. Current diagnostic methods are insufficient at identifying sequelae and lack prognostic capability. Computed tomographic angiography (CTA) is accurate for diagnosis and prognostication of pancreatitis in humans.

objectivesIn comparison to ultrasound (US), CTA will (1) better diagnose more severe pancreatitis and sequelae and (2) provide assessment of patient outcome by identification of pancreatic contrast enhancement patterns. ANIMALS: Twenty-six client-owned dogs suspected to have acute pancreatitis.

methodsUS and CTA examinations performed at time of admission were compared to determine the detection of pancreatic changes and sequelae. CTA findings also were compared to outcome indicators for prognosis of dogs with acute pancreatitis. Specific canine pancreatic lipase (cPL) samples were obtained and compared with CTA findings.

resultsTen of 26 dogs had heterogeneous contrast enhancement of the pancreas. Compared to US, CTA better identified portal vein thrombosis (P = .003). Patients with heterogeneous contrast enhancement had longer hospitalization (P = .01), including hospital stays for >5 days (P = .02), had more relapses, and were more likely to have portal vein thrombosis (P = .002). Patients with heterogeneous contrast enhancement had increased spec cPL (P = .006). CONCLUSIONS AND CLINICAL IMPORTANCE: In comparison to US, CTA better identified dogs with more severe acute pancreatitis and those with portal vein thrombosis, factors that may predict longer hospitalization and increased risk of relapse. The presence of heterogeneous contrast enhancement and portal vein thrombosis may change therapy for patients with acute pancreatitis.

Indexed as

AnimalsComputed Tomography AngiographyCross-Sectional StudiesDog DiseasesDogsFemaleLipaseMalePancreasPancreatitisProspective StudiesUltrasonographyLipaseportal vein thrombosisultrasound

Identifiers

PMID30548310
PMCPMC6335445
OpenAlexW2905400594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.