Evidence map›Paper›PMID 30547676›Full record

Trial reportCNS oncology2019

An early feasibility study of the Nativis Voyager

Charles Cobbs, Edward McClay, J Paul Duic, L Burt Nabors, Donna Morgan Murray, Santosh Kesari

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in CNS oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Neuromodulation in Neuro-Oncology: A Scoping Review.Journal of personalized medicine · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Welcome to Volume 9 ofCNS oncology · 2020
    Article
  8. Article
  9. How far will the VoyagerCNS oncology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Charles CobbsBen and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Medical Center, Seattle, WA 98122, USA.
Edward McClayMelanoma Research Center, California Cancer Associates for Research & Excellence (cCARE), San Marcos, CA 92024, USA.
J Paul DuicDepartment of Neuro-oncology, New York University, Winthrop, Mineola, NY 11501, USA.
L Burt NaborsDivision of Neuro-oncology, University of Alabama, Birmingham, AL 35294, USA.
Donna Morgan MurrayNativis, Inc., Seattle, WA 98109, USA.
Santosh KesariDepartment of Translational Neuro-Oncology and Neurotherapeutics, John Wayne Cancer Institute & Pacific Neuroscience Institute, Santa Monica, CA 90404, USA.
California Cancer Associates for Research and Excellence · USNew York University · USSaint John's Health Center · USSwedish Medical Center · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimEvaluation of the Nativis Voyager MATERIALS &

methodsVoyager is a noninvasive, nonthermal, nonionizing and portable investigational device which delivers ultra-low radio frequency energy (ulRFE

resultsData from the first 11 patients treated are reported here. Median progression-free survival was 10 weeks in the V arm and 16 weeks in the V + SoC arm. Median overall survival was 16 months in V arm and 11 months in the V + SoC arm. No serious adverse events associated with the device were reported.

conclusionThese data suggest that the Voyager is safe and feasible for the treatment of rGBM.

Indexed as

Magnetic Field TherapyAdultBrainBrain NeoplasmsCohort StudiesFeasibility StudiesFemaleGlioblastomaHumansMaleMiddle AgedNeoplasm Recurrence, LocalSurvival AnalysisTreatment OutcomeUnited Statesbrain tumorclinical trialsmedical devicenovel therapyrecurrent GBMultra-low radiofrequency energy

Identifiers

PMID30547676
PMCPMC6499016
OpenAlexW2904336534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.