Evidence map›Paper›PMID 30547387›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2019

High Dose Prednisolone Lowers Plasma Glycated Albumin Levels Compared to Actual Glycemic Control: A Retrospective Observational Study.

Masami Mizuno, Katsumi Iizuka, Takuma Ishihara, Shusaku Fukaya, Shunji Yoshida, Jun Takeda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Masami MizunoDivision of Rheumatology, Department of Internal Medicine, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
Katsumi IizukaDepartment of Diabetes and Endocrinology, Graduate School of Medicine, Gifu University, Gifu, 501-1194, Japan. kiizuka@gifu-u.ac.jp.ORCID http://orcid.org/0000-0002-9837-6238
Takuma IshiharaGifu University Hospital Innovative and Clinical Research Promotion Center, 1-1 Yanagido, Gifu, 501-1194, Japan.
Shusaku FukayaDivision of Rheumatology, Department of Internal Medicine, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
Shunji YoshidaDivision of Rheumatology, Department of Internal Medicine, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.
Jun TakedaDepartment of Diabetes and Endocrinology, Graduate School of Medicine, Gifu University, Gifu, 501-1194, Japan.
Fujita Health University · JPGifu University Hospital · JPGifu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlycated hemoglobin (A1c) and glycated albumin (GA) are often used as indicators of glycemic control. In this study, we determined whether prednisolone (PSL) administration lowers plasma GA.

methodsWe investigated the factors affecting GA using multivariate analysis in 48 subjects with connective tissue diseases (CTDs).

resultsMultiple regression analysis of GA showed that the dose of PSL [β = - 1.36; 95% confidence interval (CI) - 2.59 to - 0.14; p = 0.03], age (β = 0.06; 95% CI 0.03-0.09; p < 0.001), body mass index (BMI) (β = - 0.14; 95% CI - 0.28 to - 0.01; p = 0.042), and A1c (β = 1.4; 95% CI 0.38-2.42; p = 0.008) significantly correlated with GA (adjusted R

conclusionHigh dose (≥ 5 mg) PSL reduces GA concentration more than glycemia.

Indexed as

Connective tissue diseasesGlycated albuminGlycated hemoglobinPrednisolone

Identifiers

PMID30547387
PMCPMC6349290
OpenAlexW2905085741

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.