ArticleJournal of clinical immunology2019
Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group.
Article in Journal of clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Management of Adult Bronchiectasis: Consensus-Based Guidelines of the German Respiratory Society.Respiration; international review of thoracic diseases · 2026Guideline
- Bronchiectasis in renal transplant patients: a narrative review.BMJ open respiratory research · 2026Review
- Granulomatous lymphocytic interstitial lung disease in common variable immune deficiency: an in-depth clinical, immunological, functional and radiological exploration with a focus on its management, challenged by chronic CMV infection.Frontiers in immunology · 2025Article
- Primary immunodeficiency diseases of adults: a review of pulmonary complication imaging findings.European radiology · 2024Review
- Multiple-breath washout to detect lung disease in patients with inborn errors of immunity.ERJ open research · 2024Article
- Rituximab Monotherapy Is Effective as First-Line Treatment for Granulomatous Lymphocytic Interstitial Lung Disease (GLILD) in CVID Patients.Journal of clinical immunology · 2023Article
- Current Issues in the Management of IgG Subclass Deficiencies in Adults With Chronic Respiratory Diseases.Allergy, asthma & immunology research · 2023Review
- Hypogammaglobulinemia in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2023Article
- Retrospective evaluation of adults with primary immunodeficiency disease.Postepy dermatologii i alergologii · 2022Article
- Predictive Factors for and Complications of Bronchiectasis in Common Variable Immunodeficiency Disorders.Journal of clinical immunology · 2022Observational
- Integrating Clinics, Laboratory, and Imaging for the Diagnosis of Common Variable Immunodeficiency-Related Granulomatous-Lymphocytic Interstitial Lung Disease.Frontiers in immunology · 2022Article
- Primary Antibody Deficiencies With Pulmonary Complications: A Single-Center Experience.Cureus · 2022Article
- Pulmonary Manifestations of Primary Humoral Deficiencies.Canadian respiratory journal · 2022Review
- Multiple Breath Washout for Early Assessment of Pulmonary Complications in Patients With Primary Antibody Deficiencies: An Observational Study in Pediatric Age.Frontiers in pediatrics · 2022Article
- State-of-the-art diagnostic evaluation of common variable immunodeficiency.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021Review
- Adult Primary Antibody Deficiencies and the Lung.Turkish thoracic journal · 2021Article
- Granulomatous Lymphocytic Interstitial Lung Disease (GLILD) in Common Variable Immunodeficiency (CVID): A Multicenter Retrospective Study of Patients From Italian PID Referral Centers.Frontiers in immunology · 2021Article
- Chronic Lung Disease in Primary Antibody Deficiency: Diagnosis and Management.Immunology and allergy clinics of North America · 2020Review
- Analysis of Granulomatous Lymphocytic Interstitial Lung Disease Using Two Scoring Systems for Computed Tomography Scans-A Retrospective Cohort Study.Frontiers in immunology · 2020Article
- Interstitial lung disease in patients with common variable immunodeficiency disorders: several different pathologies?Clinical and experimental immunology · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
47 authors at 20 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies of chest computed tomography (CT) in patients with primary antibody deficiency syndromes (ADS) suggest a broad range of bronchial pathology. However, there are as yet no multicentre studies to assess the variety of bronchial pathology in this patient group. One of the underlying reasons is the lack of a consensus methodology, a prerequisite to jointly document chest CT findings. We aimed to establish an international platform for the evaluation of bronchial pathology as assessed by chest CT and to describe the range of bronchial pathologies in patients with antibody deficiency. Ffteen immunodeficiency centres from 9 countries evaluated chest CT scans of patients with ADS using a predefined list of potential findings including an extent score for bronchiectasis. Data of 282 patients with ADS were collected. Patients with common variable immunodeficiency disorders (CVID) comprised the largest subgroup (232 patients, 82.3%). Eighty percent of CVID patients had radiological evidence of bronchial pathology including bronchiectasis in 61%, bronchial wall thickening in 44% and mucus plugging in 29%. Bronchiectasis was detected in 44% of CVID patients aged less than 20 years. Cough was a better predictor for bronchiectasis than spirometry values. Delay of diagnosis as well as duration of disease correlated positively with presence of bronchiectasis. The use of consensus diagnostic criteria and a pre-defined list of bronchial pathologies allows for comparison of chest CT data in multicentre studies. Our data suggest a high prevalence of bronchial pathology in CVID due to late diagnosis or duration of disease.
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