Evidence map›Paper›PMID 30547320›Full record

ArticleJournal of cancer research and clinical oncology2019

Melanoma tumour vasculature heterogeneity: from mice models to human.

Vincent Pautu, Adélie Mellinger, Pauline Resnier, Elise Lepeltier, Ludovic Martin, Lise Boussemart, Franck Letournel, Catherine Passirani, Nicolas Clere

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of cancer research and clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Vincent PautuUMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.
Adélie MellingerUMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.
Pauline ResnierUMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.
Elise LepeltierUMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.
Ludovic MartinCHU Angers, 4 rue Larrey, 49933, Angers, France.
Lise BoussemartDepartment of Dermatology, Pontchaillou Hospital, CHU de Rennes, 35000, Rennes, France.
Franck LetournelUMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.
Catherine PassiraniUMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France.
Nicolas ClereUMR Inserm 1066, CNRS 6021, Université d'Angers, CHU, IBS, IRIS, MINT, UNIV Angers, INSERM, CNRS, Université Bretagne Loire, IBS-CHU, 4, rue Larrey, 49933, Angers, France. nicolas.clere@univ-angers.fr.ORCID http://orcid.org/0000-0002-6008-597X
Centre National de la Recherche Scientifique · FRCentre Hospitalier Universitaire d'Angers · FR

Funding

Erasmus+ 2015Ligue Contre le Cancer 2016
6 · The paper itself

Abstract

Tumour angiogenesis is defined by an anarchic vasculature and irregularities in alignment of endothelial cells. These structural abnormalities could explain the variability in distribution of nanomedicines in various tumour models. Then, the main goal of this study was to compare and to characterize the tumour vascular structure in different mouse models of melanoma tumours (B16F10 and SK-Mel-28) and in human melanomas from different patients. Tumours were obtained by subcutaneous injection of 10

Indexed as

AnimalsHumansMelanomaMelanoma, ExperimentalMiceNeovascularization, PathologicEndotheliumMelanomaMicrocirculationTumour vasculature heterogeneity

Identifiers

PMID30547320
PMCPMC11810295
OpenAlexW2903777585

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.