Evidence map›Paper›PMID 30547106›Full record

ArticleeNeurologicalSci2018

Building a network for multicenter, prospective research of central nervous system infections in South America: Process and lessons learned.

Christina Nelson, Nicanor Mori, Thanh Ton, Joseph Zunt, Meningoencephalitis Working Group, T Kochel, A Romero, N Gadea, D Tilley, E Ticona and 20 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeurologicalSci, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Christina NelsonFogarty International Center, National Institutes of Health, Bethesda, MD, USA.
Nicanor MoriFogarty International Center, National Institutes of Health, Bethesda, MD, USA.
Thanh TonDepartment of Neurology, School of Medicine, University of Washington, Seattle, WA, USA.
Joseph ZuntDepartment of Neurology, School of Medicine, University of Washington, Seattle, WA, USA.
Meningoencephalitis Working Group
T KochelUS Naval Medical Research Unit-6, Callao, Peru.
A RomeroUS Naval Medical Research Unit-6, Callao, Peru.
N GadeaUS Naval Medical Research Unit-6, Callao, Peru.
D TilleyUS Naval Medical Research Unit-6, Callao, Peru.
E TiconaDos de Mayo Hospital, Lima, Peru.
J SoriaDos de Mayo Hospital, Lima, Peru.
V CelisHospital Belen, Trujillo, Peru.
D HuancaHospital Edgardo Rebagliati Martins, Lima, Peru.
A DelgadoHospital Edgardo Rebagliati Martins, Lima, Peru.
M RivasHospital San Bartolome, Lima, Peru.
M StiglichHospital San Bartolome, Lima, Peru.
M SihuinchaHospital Cesar Garayar García, Loreto, Peru.
G DonayreHospital Felipe Santiago Arriola Iglesias, Loreto, Peru.
J CelisHospital Felipe Santiago Arriola Iglesias, Loreto, Peru.
R RomeroHospital Daniel Alcides Carrion, Callao, Peru.
N TamHospital Daniel Alcides Carrion, Callao, Peru.
M TipismanaHospital Cayetano Heredia, Lima, Peru.
I EspinozaHospital Cayetano Heredia, Lima, Peru.
M RozasHospital Regional Cusco, Cusco, Peru.
A PeraltaHospital Carlos Alberto Seguin, Arequipa, Peru.
E SanchezHospital Hipolito Unanue, Lima, Peru.
L VasquezHospital Hipolito Unanue, Lima, Peru.
P MuñozHospital Hipolito Unanue, Lima, Peru.
G RamirezHospital Emergencias Pediatricas, Lima, Peru.
I ReyesHospital Emergencias Pediatricas, Lima, Peru.

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
Retrovial Infections of the Nervous System in PeruR01NS055627 · NINDS · UNIVERSITY OF WASHINGTON · PI ZUNT, JOSEPH RAYMOND · 2006 to 2010
$3.0M
FIC NIH HHS R24 TW007988NINDS NIH HHS R01 NS055627
6 · The paper itself

Abstract

Multicenter collaborative networks are essential for advancing research and improving clinical care for a variety of conditions. Research networks are particularly important for central nervous system infections, which remain difficult to study due to their sporadic occurrence and requirement for collection and testing of cerebrospinal fluid. Establishment of long-term research networks in resource-limited areas also facilitates diagnostic capacity building, surveillance for emerging pathogens, and provision of appropriate treatment where needed. We review our experience developing a research network for encephalitis among twelve hospitals in five Peruvian cities since 2009. We provide practical suggestions to aid other groups interested in advancing research on central nervous system infections in resource-limited areas.

Indexed as

Central nervous system infectionsEncephalitisEpidemiologyHerpes simplex virusVirology

Identifiers

PMID30547106
PMCPMC6284170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.