Evidence map›Paper›PMID 30547105›Full record

ArticleeNeurologicalSci2018

Evaluating layered stigma from comorbid HIV and epilepsy among Zambian adults.

Melissa A Elafros, Joseph C Gardiner, Izukanji Sikazwe, Jason F Okulicz, Nigel Paneth, Elwyn Chomba, Gretchen L Birbeck

Open access · goldAbstract read
In one paragraph

Article in eNeurologicalSci, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Melissa A ElafrosInternational Neurologic and Psychiatric Epidemiology Program, Michigan State University, 909 Fee Road, Room 324, East Lansing, MI 48824, USA.
Joseph C GardinerDepartment of Epidemiology and Biostatistics, Michigan State University, 909 Fee Road, Room B629, East Lansing, MI 48824, USA.
Izukanji SikazweCentre for Infectious Disease Research in Zambia, 532 Great North Road, PO Box 24681, Lusaka, Zambia.
Jason F OkuliczInfectious Disease Service, Brooke Army Medical Center, 3851 Roger Brooke Dr., Fort Sam Houston, TX 78234, USA.
Nigel PanethDepartment of Epidemiology and Biostatistics, Michigan State University, 909 Fee Road, Room B629, East Lansing, MI 48824, USA.
Elwyn ChombaUniversity Teaching Hospital, Department of Paediatrics and Child Health, Nationalist Way, Lusaka, Zambia.
Gretchen L BirbeckStrong Epilepsy Center, Department of Neurology, University of Rochester, 265 Crittenden Blvd, CU420694, Rochester, NY 14642, USA.
Michigan State University · USBrooke Army Medical Center · USCentre for Infectious Disease Research in Zambia · ZMUniversity of Rochester · USUniversity Teaching Hospital · ZM

Funding

Cohort of HIV-Associated Seizures and Epilepsy in Zambia (CHASE): Scale up and expansion informed by R21 FindingsR01NS094037 · NINDS · UNIVERSITY OF ROCHESTER · PI BIRBECK, GRETCHEN L., SIKAZWE, IZUKANJI · 2015 to 2019
$3.0M
A Cohort Study of Seizures and Epilepsy in HIV+ Zambian AdultsR21NS073509 · NINDS · MICHIGAN STATE UNIVERSITY · PI BIRBECK, GRETCHEN L. · 2011 to 2012
$245k
NINDS NIH HHS R01 NS094037NINDS NIH HHS R21 NS073509
6 · The paper itself

Abstract

background and purposeStigma hinders care for patients with neurologic illness. Layered stigma due to comorbid disease is common yet poorly characterized due to lack of instruments. Epilepsy and HIV are prototypical stigmatized conditions widespread in sub-Saharan Africa.

methodsWe assessed layered stigma among people with HIV and epilepsy (n = 21), epilepsy only (n = 88), and HIV only (n = 40) in Zambia. Epilepsy-associated stigma was assessed using the Stigma Scale of Epilepsy and Jacoby's Stigma Scale. HIV-related stigma was assessed using the HIV/AIDS Stigma Instrument-People Living with HIV/AIDS and Jacoby's Stigma Scale. Stigma was compared across groups using

results55% (60/109) with epilepsy reported some epilepsy-associated stigma and 20% (12/61) with HIV reported HIV self-stigmatization. Those with HIV and epilepsy were more likely to associate seizures with fear (OR 6.1 [95% CI: 1.3-27.9]) and epilepsy with dependence (OR 4.6 [1.1-19.6]), controlling for age, gender, marital status, and employment. Those with comorbid disease were more likely to report they were "no longer a person" and felt "blamed" for their HIV. Controlling for age and gender, the difference in depersonalization remained (OR: 6.4 [1.1-36.1]).

conclusionIndividuals carrying the burden of one stigmatized condition may be more vulnerable to stigma from a comorbid disease.

Indexed as

Double stigmaIntersectional stigmaResource-limited settingSub-Saharan AfricaVulnerable populations

Identifiers

PMID30547105
PMCPMC6284156
OpenAlexW2776085205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.