Evidence map›Paper›PMID 30546966›Full record

ArticleOncoimmunology

Effect of combined anti-PD-1 and temozolomide therapy in glioblastoma.

Junseong Park, Chang Gon Kim, Jin-Kyoung Shim, Jong Hoon Kim, Hoyoung Lee, Jae Eun Lee, Min Hwan Kim, Keeok Haam, Inkyung Jung, Su-Hyung Park and 3 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. A systematic review of immunotherapy in high-grade glioma: learning from the past to shape future perspectives.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
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  3. Article
  4. Review
  5. Review
  6. Dual-action nanotherapy: Temozolomide-loaded, anti-PD-L1 scFv-functionalized lipid nanocarriers for targeted glioblastoma therapy.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2025
    Article
  7. Article
  8. Cell death in glioblastoma and the central nervous system.Cellular oncology (Dordrecht, Netherlands) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Junseong ParkDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-0436-8614
Chang Gon KimGraduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Jin-Kyoung ShimDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jong Hoon KimGraduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Hoyoung LeeBiomedical Science and Engineering Interdisciplinary Program, KAIST, Daejeon, Republic of Korea.
Jae Eun LeeDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Min Hwan KimGraduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.
Keeok HaamDepartment of Biological Sciences, KAIST, Daejeon, Republic of Korea.
Inkyung JungDepartment of Biological Sciences, KAIST, Daejeon, Republic of Korea.
Su-Hyung ParkGraduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.ORCID 0000-0003-0436-8614
Jong Hee ChangDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0003-1509-9800
Eui-Cheol ShinGraduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea.ORCID 0000-0002-6308-9503
Seok-Gu KangDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-5676-2037
Korea Advanced Institute of Science and Technology · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

checkpoint inhibitorcombination therapyglioblastomaPD-1temozolomide

Identifiers

PMID30546966
PMCPMC6287793
OpenAlexW2897368980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.