Evidence map›Paper›PMID 30546437›Full record

ArticleOncology letters2018

Microbiota dysbiosis is associated with HPV-induced cervical carcinogenesis.

Wojciech Kwasniewski, Maria Wolun-Cholewa, Jan Kotarski, Wojciech Warchol, Dorota Kuzma, Anna Kwasniewska, Anna Gozdzicka-Jozefiak

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 2 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wojciech KwasniewskiDepartment of Gynaecological Oncology and Gynaecology, Medical University of Lublin, 20-081 Lublin, Poland.
Maria Wolun-CholewaDepartment of Cell Biology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Jan KotarskiDepartment of Gynaecological Oncology and Gynaecology, Medical University of Lublin, 20-081 Lublin, Poland.
Wojciech WarcholDepartment of Biophysics, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Dorota KuzmaDepartment of Molecular Virology, Adam Mickiewicz University, 61-712 Poznan, Poland.
Anna KwasniewskaDepartment of Obstetrics and Gynaecology, Medical University of Lublin, 20-081 Lublin, Poland.
Anna Gozdzicka-JozefiakDepartment of Molecular Virology, Adam Mickiewicz University, 61-712 Poznan, Poland.
Medical University of Lublin · PLAdam Mickiewicz University in Poznań · PLPoznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical microbial communities serve a crucial role in the persistence and development of oncogenic human papilloma virus (HPV) infections. In the present study, the authors hypothesised that disturbed heterogeneity of microbial flora was associated with HPV-induced carcinogenesis. Swabs of the cervical microbiota were collected from 250 women and the 16S ribosomal DNA was sequenced using a high throughput assay. The swabs of cervical microbiota were grouped according to the community state types (CSTs) as follows: Healthy cervical swabs; swabs taken from low-grade squamous intra-epithelial lesions (LSIL) and swabs taken from high-grade squamous intra-epithelial lesions (HSIL). Analysis of the bacterial classes revealed that the CST cervical swabs of the volunteers were characterised by

Indexed as

16S ribosomal DNA polymerase chain reaction-amplification and next generation sequencingcervical cancercervical microbiota

Identifiers

PMID30546437
PMCPMC6256731
OpenAlexW2892881193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.