Evidence map›Paper›PMID 30546368›Full record

ReviewFrontiers in immunology2018

Non-coding RNAs Function as Immune Regulators in Teleost Fish.

Man Wang, Shuai Jiang, Wei Wu, Fei Yu, Wenguang Chang, Peifeng Li, Kun Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Man WangInstitute for Translational Medicine, Medical College of Qingdao University, Qingdao, China.
Shuai JiangKey Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Wei WuInstitute for Translational Medicine, Medical College of Qingdao University, Qingdao, China.
Fei YuInstitute for Translational Medicine, Medical College of Qingdao University, Qingdao, China.
Wenguang ChangInstitute for Translational Medicine, Medical College of Qingdao University, Qingdao, China.
Peifeng LiInstitute for Translational Medicine, Medical College of Qingdao University, Qingdao, China.
Kun WangInstitute for Translational Medicine, Medical College of Qingdao University, Qingdao, China.
Qingdao University · CNInstitute of Oceanology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs (ncRNAs) are functional RNA molecules that are transcribed from DNA but not translated into proteins. ncRNAs function as key regulators of gene expression and chromatin modification. Recently, the functional role of ncRNAs in teleost fish has been extensively studied. Teleost fish are a highly diverse group among the vertebrate lineage. Fish are also important in terms of aquatic ecosystem, food production and human life, being the source of animal proteins worldwide and models of biomedical research. However, teleost fish always suffer from the invasion of infectious pathogens including viruses and bacteria, which has resulted in a tremendous economic loss to the fishing industry worldwide. Emerging evidence suggests that ncRNAs, especially miRNAs and lncRNAs, may serve as important regulators in cytokine and chemokine signaling, antigen presentation, complement and coagulation cascades, and T cell response in teleost fish. In this review, we summarize current knowledge and understanding of the roles of both miRNAs and lncRNAs in immune regulation in teleost fish. Molecular mechanism insights into the function of ncRNAs in fish immune response may contribute to the development of potential biomarkers and therapeutic targets for the prevention and treatment of fish diseases.

Indexed as

AnimalsCytokinesFish DiseasesFishesFish ProteinsHumansMicroRNAsRNA, Long NoncodingSignal TransductionCytokinesFish ProteinsMicroRNAsRNA, Long Noncodingfishimmune regulatorimmune responseinfectious pathogennon-coding RNA

Identifiers

PMID30546368
PMCPMC6279911
OpenAlexW2902621431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.